Evaluate the sero-epidemiology of Toxoplasma gondii in patients referred to Ghaem hospital, Mashhad, Iran

sharifi, karam and Sharifi, Karim and Hoseini Farrash, Razieh and Khaledi, Azad (2018) Evaluate the sero-epidemiology of Toxoplasma gondii in patients referred to Ghaem hospital, Mashhad, Iran. Navid No, 21 (65). pp. 42-48.

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Abstract

Abstract Introduction: Toxoplasma gondii is an obligate intracellular protozoan with a global prevalence, which infects a wide range of hosts such as humans, domestic mammals, and birds. Humans and other vertebrates are indirectly infected with the parasite through ingesting oocytes. We aimed to evaluate the sero-epidemiology of Toxoplasma gondii in patients visiting Ghaem Hospital, Mashhad, Iran, in 2015. Materials and Methods: We performed a descriptive cross-sectional study of 306 patients visiting Ghaem Hospital, Mashhad, Iran, in 2015. In case of the patients� consent, a demographics form was completed by a trained individual, and 5 cc of blood was simultaneously drawn for the detection of toxoplasmosis. The blood samples were centrifuged at 2000 rpm for 10 min. Then, ELISA was carried out for measuring the anti-Toxoplasma gondii immunoglobulin G (IgG) and immunoglobulin M (IgM). Finally, to analyze the data, t-test and Fisher�s exact test were run in SPSS, version 22. Results: The mean age of the patients was 25.56±5.8 years. Of the 306 patients, 270 (88.2) were female and 36 (11.8) were male. We found a significant relationship between age and the prevalence of Toxoplasma gondii (P<0.05). However, there was no significant association between gender and the prevalence of this parasite (P�0.05). The overall prevalence of IgG specific for T. gondii was 34, this rate among women and men was 34.4 and 33.6, respectively. In total, the prevalence of IgM for T. gondii was 6.6. Conclusion: Our study showed that the seroprevalence of toxoplasmosis in Mashhad, like other regions of Iran, is high. Thus, preventive measures should be adopted

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Journals > Navid No
Depositing User: nnj nnj
Date Deposited: 03 Jul 2018 13:52
Last Modified: 03 Jul 2018 13:52
URI: http://eprints.mums.ac.ir/id/eprint/10095

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