Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’s Striae: A Contralateral Eye Study

Sedaghat, M.R and Ostadi-moghddam, H and Asgarizadeh, F and Narooie-noori, F and Rajabi, S and Rakhshandadi, T and Hashemian, H (2018) Comparative Evaluation of Topographic Characteristics in Bilateral Keratoconus with Unilateral Corneal Vogt’s Striae: A Contralateral Eye Study. Journal of Paramedical Sciences & Rehabilitation, 7 (3). pp. 7-16.

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Abstract

Purpose: The aim of this study was to evaluate and compare topographic characteristics in bilateral keratoconus (KCN) patients with unilateral Vogt’s striae. Methods: In this prospective cross-sectional contralateral eye study, the KCN patients that were enrolled in this study had a reliable diagnosis of bilateral clinical KCN with unilateral Vogt`s striae based on slit-lamp signs, as well as corneal topographic/tomographic maps. All the cases underwent a comprehensive ophthalmic examination, including uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA),cycloplegic refraction (calculated by vectorial analysis), and placido disc-based Tomey topographer (TMS-4; Tomey, Germany). In this study, clinical and topographic characteristics of all cases were evaluated and compared between the contralateral KCN eyes with Vogt`s striae and those without Vogt`s striae. Paired sample t-test was used to compare the parameters with a normal distribution and the Wilcoxon signed rank test was used to compare the non-parametric parameters. P-value Results: Fifty patientsaged 20 to 38 years (27.43±5.46) were recruited in this study. Our results showed that there were significant differences in sphere, cylinder, spherical equivalent, UDVA, CDVA and J0 (all p<0.001) except for J45 (p=0.58) between the contralateral eyes of KCN patients. In KCN eyes with Vogt’s striae, flat (46.48±3.33 vs 44.44±2.22, p<0.001), steep (52.48±4.39 vs 47.02±3.26, p<0.001), minimum (46.36±3.37 vs 44.35±2.17, p<0.001) and average keratometry (49.27±3.96 vs 45.74±2.60, P<0.001) as well as Surface Regularity Index (1.39±1.12 vs 0.52±0.41, p<0.001), Surface Asymmetry Index (2.32±1.25 vs 1.42±1.04, P<0.001), Keratoconus Index (75.07±28.83 vs 48.01±33.52, p<0.001) and Keratoconus Severity Index (65.88±22.25 vs 38.61±29.40, p<0.001)were higher than the contralateral eye without Vogt’s striae. Conclusion: Corneal topographic parameters showed a significant difference between the contralateral KCN eyes with and without Vogt’s striae. These results should be noticed in clinical evaluations and treatments of KCN patients.

Item Type: Article
Subjects: WW Ophthalmology
Divisions: Journals > Journal of Paramedical Science and Rehabilitation
Depositing User: jpsr jpsr
Date Deposited: 11 Sep 2018 05:00
Last Modified: 11 Sep 2018 05:00
URI: http://eprints.mums.ac.ir/id/eprint/10237

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