The Comparison of 8 week combined training with two different intensity on level of serum Irisin, and glycemic indices of type 2 diabetic women

Enteshary, Mahtab and Esfarjani, Fahimeh and Reisi, Jalil (2018) The Comparison of 8 week combined training with two different intensity on level of serum Irisin, and glycemic indices of type 2 diabetic women. medical journal of mashhad university of medical sciences, 61 (2). pp. 971-984.

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Abstract

Introduction: Irisin is a myokine released from a membrane protein FNDC5 and has positive effects on carbohydrate metabolism. The aim of this study was to compare the effect of two different intensities of combined training on serum irisin, FBS, HbA1c and insulin resistance. Materials and Methods: 26 patients with type 2 diabetes mellitus were divided into 3 groups, intense and moderate combined exercise and control group. The training groups participated in combination exercises with high or moderate intensity for 8 weeks. Exercise aerobic moderate intensity performed with 70 to 89 of HRmax, 75 minutes per week. Addition 2 day strength training with elastic band. Moderate exercise aerobic exercises were performed at 55-69 of HRmax, 150 minutes per week. and resistance training two days a week with elastic band. Blood samples were taken before exercise and 48 hours after the last session. Results: Combined exercise leading to increased irisin, decrease fasting blood glucose, HbA1c, and decreased insulin resistance in both experimental groups (P<0.05). Although the increase irisin hormone in intense training group was more than moderate group, but there was no significant difference in fasting blood glucose, HbA1c and insulin resistance between the two groups (P<0.05). Conclusion: Combined exercises are beneficial for increasing the level of irisin, reducing fasting blood glucose, HbA1c and decreasing insulin resistance, and therefore controlling diabetes. Moderate combination exercises can be used to improve glycemic conditions as an efficient method.

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