Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments

Mirsadraee, Majid and Tavakoli, Afsaneh and Ghorani, Vahideh and Ghafari, Shadi (2018) Effects of Rosmarinus officinalis and Platanus orientalis extracts on asthmatic subjects resistant to routine treatments. Avicenna Journal of Phytomedicine, 8 (5). pp. 399-407.

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Abstract

Objective: The present study aimed to determine the effects of Rosmarinus officinalis (R. officinalis) and Platanus orientalis(P. orientalis) extracts on asthma. Materials and Methods: We conducted a randomized, double-blind, active-comparator study to evaluate the effect of P. orientalis and R. officinalis extracts on asthmatic patients resistant to routine treatment.The subjects were randomly divided into three groups receiving P. orientalis and R. officinalis extracts alone or in combination. The primary endpoints were clinical findings, spirometry, exhaled nitric oxide (FENO) and Asthma Control Test (ACT) assessed over the one-month treatment period. Results: ACT score showed significant improvement after treatment with R. officinalis (p<0.05) but not with P. orientalis. Clinical evaluations showed that cough, sputum production and wheezing were significantly improved in R. officinalis group (p Conclusion: R. officinalis extract showed promising results in treatment of resistant asthma. Further studies to find the most effective components of these herbal medicines are recommended.

Item Type: Article
Subjects: WF Respiratory System
QT physiology
QV pharmacology
Divisions: Journals > Avicenna J Phytomedicine
Depositing User: ajp ajp
Date Deposited: 26 Dec 2018 10:20
Last Modified: 26 Dec 2018 10:20
URI: http://eprints.mums.ac.ir/id/eprint/10728

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