Comparative virulotyping and phylogenomics of Escherichia coli isolates from urine samples of men and women suffering urinary tract infections

Staji, Hamid and Rassouli, Maryam and Jourablou, Samaneh (2019) Comparative virulotyping and phylogenomics of Escherichia coli isolates from urine samples of men and women suffering urinary tract infections. Iranian Journal of Basic Medical Sciences, 22 (2). pp. 211-214.

[img] Text
IJBMS_Volume 22_Issue 2_Pages 211-214.pdf

Download (443kB)
Official URL: http://ijbms.mums.ac.ir/article_11915.html

Abstract

Objective(s): Escherichia coli strains are common pathogens that can cause urinary tract infections (UTI). This study aimed to assess E. coli phylogroups and virulence types in male and female UTI patients.Materials and Methods: In the present study, 160 uropathogenic E. coli (UPEC) isolates (from both sexes) were assigned to phylogroups/types and some extraintestinal virulence factors were detected within them by multiplex-PCR.Results: The isolates from women and men were predominantly distributed within phylogroup B2 and D, respectively. The presence of D2 phylotype was higher in men isolates than women, significantly (P=0.045). In male isolates papEF and sfa/focDE are more prevalent in B2 group than D, significantly (P=0.048; P=0.035). The prevalence of hly in B2 group is significantly higher than D (P=0.034) in female isolates.Conclusion: This study highlighted different features of E. coli genotypes from phylogenetic and virulence point of view implicated in UTI’s in both human genders.

Item Type: Article
Subjects: QW Microbiology and Immunology
Divisions: Journals > Iranian J Basic Medical Sciences
Depositing User: ijbms ijbms
Date Deposited: 07 Jan 2019 09:28
Last Modified: 07 Jan 2019 09:28
URI: http://eprints.mums.ac.ir/id/eprint/10983

Actions (login required)

View Item View Item