SPECT-CT fusion in the diagnosis of hyperparathyroidism

Monzen, Yoshio and Tamura, Akihisa and Okazaki, Hajime and Kurose, Taichi and Kobayashi, Masayuki and Kuraoka, Masatsugu (2015) SPECT-CT fusion in the diagnosis of hyperparathyroidism. Asia Oceania Journal of Nuclear Medicine and Biology, 3 (1). pp. 61-65.

AOJNMB_Volume 3_Issue 1_Pages 61-65.pdf

Download (518kB) | Preview
Official URL: http://aojnmb.mums.ac.ir/article_3163.html


Objective(s): In this study, we aimed to analyze the relationship between the diagnostic ability of fused single photon emission computed tomography/computed tomography (SPECT/CT) images in localization of parathyroid lesions and the size of adenomas or hyperplastic glands. Methods: Five patients with primary hyperparathyroidism (PHPT) and 4 patients with secondary hyperparathyroidism (SHPT) were imaged 15 and 120 minutes after the intravenous injection of technetium99mmethoxyisobutylisonitrile (99mTc-MIBI). All patients underwent surgery and 5 parathyroid adenomas and 10 hyperplastic glands were detected. Pathologic findings were correlated with imaging results. Results: The SPECT/CT fusion images were able to detect all parathyroid adenomas even with the greatest axial diameter of 0.6 cm. Planar scintigraphy and SPECT imaging could not detect parathyroid adenomas with an axial diameter of 1.0 to 1.2 cm. Four out of 10 (40) hyperplastic parathyroid glands were diagnosed, using planar and SPECT imaging and 5 out of 10 (50) hyperplastic parathyroid glands were localized, using SPECT/CT fusion images. Conclusion: SPECT/CT fusion imaging is a more useful tool for localization of parathyroid lesions, particularly parathyroid adenomas, in comparison with planar and or SPECT imaging.

Item Type: Article
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Asia Oceania J Nuclear Medicine & Biology
Depositing User: AOJNMB AOJNMB
Date Deposited: 19 Sep 2017 13:50
Last Modified: 19 Sep 2017 13:50
URI: http://eprints.mums.ac.ir/id/eprint/1151

Actions (login required)

View Item View Item