The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study

Keikha, Masoud and Karbalaei Zadeh Babaki, mohsen and Marcondes Fonseca, Luiz Augusto and Casseb, Jorge (2019) The Relevance of HTLV-1-associated Myelopathy/Tropical Spastic Paraparesis in Iran: A Review Study. Reviews in Clinical Medicine, 6 (2). pp. 60-65.

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Abstract

Human T-cell lymphotropic virus type I (HTLV-I) is a retrovirus, which is the causative agent of adult T-cell leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Evidence suggests that the interaction of HTLV-1 with the cellular-immune system plays a key role in the development of HAM/TSP. However, the main mechanism in this regard remains unknown. The present study aimed to review the HAM/TSP pathogenesis, current status of HTLV-1 in Iran, and available treatments for HTLV-1 infection.

Item Type: Article
Uncontrolled Keywords: Infectious Disease,HTLV-1,HAM/TSP
Subjects: QW Microbiology and Immunology
Divisions: Journals > Reviews in Clinical Medicine
Depositing User: RCM RCM
Date Deposited: 31 Jul 2019 06:53
Last Modified: 31 Jul 2019 06:53
URI: http://eprints.mums.ac.ir/id/eprint/11868

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