Multi-drug resistant Staphylococcus aureus isolated from emergency ward of an Iranian hospital

Ahmadi, K. and Zakeri, H. and Doloo, H. Z. M. and Kakhki, B. R. and Mohammadshahi, A. and Alavi-Moghaddam, M. and Hashemian, A. M. (2016) Multi-drug resistant Staphylococcus aureus isolated from emergency ward of an Iranian hospital. Tropical Journal of Pharmaceutical Research, 15 (4). pp. 815-819.

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Abstract

Purpose: To study the prevalence of resistant strains of S. aureus isolated from surfaces, beds and various equipment of an Iranian hospital emergency ward. Methods: Two hundred swab samples were collected from the surfaces, beds, trolleys, surgical equipment and diagnostic medical devices in emergency ward. Samples were cultured and those that were S. aureus-positive were confirmed using polymerase chain reaction (PCR). Antimicrobial resistance pattern was analyzed using disk diffusion method. Results: Nine of 200 samples (4.5 ) collected were positive for S. aureus. Surfaces (8.8 ), beds (5 ) and trolleys (5 ) were the most commonly contaminated. S. aureus isolates exhibited varying levels of resistance against antibiotics with the following being the highest: tetracycline (88.8 ), penicillin (88.8 ) and ampicillin (77.7 ). The prevalence of resistance against methicillin, oxacillin and azithromycin were 44.4, 33.3 and 33.3 , respectively. There was no pattern of resistance against imipenem. Conclusion: Efficient disinfection of surfaces, beds, trolleys and surgical instruments should be performed periodically to reduce colonization of resistant strains of S. aureus in various areas of emergency health care centers. © Pharmacotherapy Group, Faculty of Pharmacy, University of Benin, Benin City, 300001 Nigeria. All rights reserved.

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 Correspondence Address: Hashemian, A.M.; Department of Emergency Medicine, Mashhad University of Medical SciencesIran; email: HashemianAM@mums.ac.ir
Uncontrolled Keywords: Antibiotic resistance Emergency ward Hospital equipment Nocosomial infection Staphylococcus aureus ampicillin azithromycin cefixime clindamycin cotrimoxazole imipenem meticillin norfloxacin oxacillin penicillin derivative RNA 16S tetracycline antibiotic sensitivity Article bacterial strain bacterium identification bacterium isolate bacterium isolation controlled study disk diffusion DNA extraction gel electrophoresis hospital infection methicillin resistant Staphylococcus aureus multidrug resistance multidrug resistant Staphylococcus aureus nonhuman polymerase chain reaction prevalence
Subjects: QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 03 Mar 2020 10:42
Last Modified: 03 Mar 2020 10:42
URI: http://eprints.mums.ac.ir/id/eprint/12900

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