Does abstinence resolve poor sleep quality in former methamphetamine dependents?

Ardani, A. R. and Saghebi, S. A. and Nahidi, M. and Zeynalian, F. (2016) Does abstinence resolve poor sleep quality in former methamphetamine dependents? Sleep Science, 9 (3). pp. 255-260.

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Background and objective Among substances that have a significant effect on sleep are stimulants, including amphetamines. As there are few studies assessing sleep quality in methamphetamine withdrawal this study aims to evaluate changes in sleep quality of methamphetamine dependent patients during early remission period by controlling depression and anxiety as confounding variables. Methods This study was conducted in Mashhad, Iran. Ninety amphetamine dependent patients, who were admitted in residential centers during 2012-2014 and met our inclusion criteria, were chosen by purposive nonprobability sampling method. Sleep quality was assessed by Pittsburg sleep questionnaire, in the first, second, and after the fourth week of abstinence. Additionally all participants were assessed by Beck Depression Inventory-2 and Beck Anxiety Inventory for controlling depressive and anxiety symptoms. Results The prevalence of improper quality of sleep was very high (97.8) within the first week of withdrawal, but it reduced considerably four weeks after abstinence (52.2), which was statistically significant (P=0.00). The variations of depression and anxiety levels within four weeks after quitting methamphetamine, have low impact on variation of patients' sleep quality (adjusted R2<0.5). Furthermore, the effectiveness of these two intervening variables on patients' quality of sleep was dwindled over time after abstinence. Conclusions This study showed that the patients' quality of sleep improved significantly four weeks after abstinence and its variation was independent from variations in anxiety and depressive symptoms. © 2016 Brazilian Association of Sleep.

Item Type: Article
Additional Information: Cited By :1 Export Date: 16 February 2020 Correspondence Address: Zeynalian, F.; Psychiatry and Behavioural Sciences Research Center, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: Abstinence Amphetamine Anxiety Depression Sleep quality methamphetamine adult Article Beck Anxiety Inventory Beck Depression Inventory drug withdrawal female human Iran major clinical study male methamphetamine dependence Pittsburgh Sleep Quality Index remission
Subjects: WL Nervous system
WM Psychiatry
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 03 Mar 2020 08:48
Last Modified: 03 Mar 2020 08:48

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