Excessive incidence of stroke in iran: Evidence from the mashhad stroke incidence study (MSIS), a population-based study of stroke in the middle east

Azarpazhooh, M. R. and Etemadi, M. M. and Donnan, G. A. and Mokhber, N. and Majdi, M. R. and Ghayour-Mobarhan, M. and Ghandehary, K. and Farzadfard, M. T. and Kiani, R. and Panahandeh, M. and Thrift, A. G. (2010) Excessive incidence of stroke in iran: Evidence from the mashhad stroke incidence study (MSIS), a population-based study of stroke in the middle east. Stroke, 41 (1). e3-e10.

[img] Text

Download (480kB)


BACKGROUND AND PURPOSE-: The epidemiology of stroke and its subtypes in the Middle East is unclear. Most previous studies have been performed in Western countries, and incidence rates are unlikely to apply in the Middle East. We aimed to determine the incidence of stroke in Mashhad, northeastern Iran. METHODS-: During a 12-month period (2006-2007), we prospectively ascertained all strokes occurring in a population of 450 229. Multiple overlapping sources were used to identify people with stroke. A large number of volunteers assisted in finding stroke patients not admitted to hospital. Potential cases were reviewed by a group of stroke experts before inclusion. RESULTS-: A total of 624 first-ever strokes occurred during the study period, 98.4 undergoing imaging. Despite a relatively low crude annual incidence rate of first-ever stroke FES (139; 95 CI, 128 to 149) per 100 000 residents, rates adjusted to the European population aged 45 to 84 years were higher than in most other countries: 616 (95 CI, 567 to 664) for ischemic stroke, 94 (95 CI, 75 to 113) for intracerebral hemorrhage, and 12 (95 CI, 5 to 19) for subarachnoid hemorrhage. Age-specific stroke incidence was higher in younger patients than is typically seen in Western countries. Comparison of age-specific incidence rates between regions revealed that stroke in Mashhad occurs approximately 1 decade earlier than in Western countries. CONCLUSIONS-: The results of this study provide evidence that the incidence of stroke in Iran is considerably greater than in most Western countries, with stroke occurring at younger ages. Ischemic stroke incidence was also considerably greater than reported in other regions. © 2009 American Heart Association, Inc.

Item Type: Article
Additional Information: Cited By :106 Export Date: 16 February 2020 CODEN: SJCCA Correspondence Address: Azarpazhooh, M. R.; Department of Neurology, Ghaem Hospital, Mashhad University of Medical Science (MUMS), Taghi Abad Square, Mashhad, Iran; email: azarpazhoohmr@mums.ac.ir
Uncontrolled Keywords: Cerebrovascular disorders Epidemiology Incidence Iran Middle East Population-based study Stroke adult aged article brain hemorrhage cerebrovascular accident controlled study female human imaging major clinical study male population research priority journal prospective study stroke patient subarachnoid hemorrhage Age Factors Aged, 80 and over Cohort Studies Health Services Accessibility Humans Middle Aged Prospective Studies Risk Factors
Subjects: WL Nervous system
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 03 Mar 2020 06:45
Last Modified: 03 Mar 2020 06:45
URI: http://eprints.mums.ac.ir/id/eprint/12930

Actions (login required)

View Item View Item