Paranasal sinuses malignancies: A 12-year review of clinical characteristics

Danesh-Sani, S. A. and Sarafraz, A. and Chamani, M. and Derakhshandeh, H. (2016) Paranasal sinuses malignancies: A 12-year review of clinical characteristics. Medicina Oral, Patologia Oral y Cirugia Bucal, 21 (5). e626-e630.

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Background: Inadequate epidemiologic investigations of the paranasal sinuses malignancies prompted this retrospective study with special emphasis on a major group of 111 tumors. Material and Methods: Clinical records of 111 patients with histologically confirmed malignant tumors of the paranasal sinuses were investigated retrospectively from April 2000 to January 2012. Collection of data included demographic information, clinical manifestations, treatment plans, and histopathology of the tumor. Results: There were 69 (62.16) male and 42 (37.83) female patients (male-to-female ratio of 1.6:1), with a median age of 49±12.2 years (range 21 to 88 years). A high level of occurrence was noticed in the fifth (26.3) decade of life. The most frequent histological types were squamous cell carcinoma (43.5) and adenoid cystic carcinoma (19). Among clinical manifestations, nasal obstruction was the most frequent followed by diplopia, and facial swelling. Fifty three patients (47.74) were treated with combined approach of surgery and radiation therapy. Conclusions: Paranasal sinuses malignancies are rare conditions with nonspecific symptoms which make early diagnosis of the lesions more challenging. The optimal therapeutic protocol for patients suffering from these tumors is still a somewhat controversial entity and requires further studies. © Medicina Oral S. L.

Item Type: Article
Additional Information: Cited By :7 Export Date: 16 February 2020 Correspondence Address: Danesh-Sani, S.-A.; Avicenna Research Institute, Dental Research Center, Oral and maxillofacial Surgery Division, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: Malignancy Paranasal sinuses Radiotherapy Surgery adenocarcinoma adult aged cancer localization clinical feature diplopia epistaxis exophthalmos female headache hearing disorder human lymphoma major clinical study male melanoma nose obstruction paranasal sinus cancer retrospective study Review sarcoma squamous cell carcinoma swelling very elderly adenoid cystic carcinoma complication middle aged paranasal sinus paranasal sinus tumor young adult Aged, 80 and over Carcinoma, Adenoid Cystic Carcinoma, Squamous Cell Humans Paranasal Sinus Neoplasms Retrospective Studies
Subjects: QY Clinical Pathology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 03 Mar 2020 04:42
Last Modified: 03 Mar 2020 04:42

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