Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora

Najafzadeh, M. J. and Rezusta, A. and Cameo, M. I. and Zubiri, M. L. and Yus, M. C. and Badali, H. and Revillo, M. J. and De Hoog, G. S. (2010) Successful treatment of chromoblastomycosis of 36 years duration caused by Fonsecaea monophora. Medical Mycology, 48 (2). pp. 390-393.

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We report a case of chromoblastomycosis in a 67-year-old female farmer, which involved a large (20 × 30 cm) cicatricial erythematous plaque on the inner side of her right thigh. The lesion was initially a small nodule which gradually extended over 36 years. Direct microscopic examination revealed a granulomatous lesion with muriform cells surrounded by giant cells. The mould recovered in cultures was dark olivaceous and identified as Fonsecaea monophora by ribosomal internal transcribe spacer (ITS) sequence data. The lesion was successfully cured after 4 months treatment with itraconazole, but there was a relapse. © 2010 ISHAM.

Item Type: Article
Additional Information: Cited By :30 Export Date: 16 February 2020 CODEN: MEMYF Correspondence Address: De Hoog, G. S.; Centraalbureau voor Schimmelcultures, PO Box 85167, NL-3508 AD Utrecht, Netherlands; email:
Uncontrolled Keywords: Chromoblastomycosis Fonsecaea monophora Itraconazole actin beta tubulin internal transcribed spacer aged antimicrobial therapy article case report chromomycosis clinical feature disease duration DNA sequence drug withdrawal erythema female Fonsecaea fungus culture fungus identification giant cell histopathology human human cell human tissue microscopy nucleotide sequence relapse sequence analysis skin defect skin nodule tissue structure treatment duration
Subjects: QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 01 Mar 2020 07:15
Last Modified: 01 Mar 2020 07:15

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