Central serous chorioretinopathy: From glucocorticoids to light intensity

Norouzpour, A. and Abrishami, M. (2016) Central serous chorioretinopathy: From glucocorticoids to light intensity. International Journal of Ophthalmology, 9 (2). pp. 312-314.

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Central serous chorioretinopathy (CSC) is characterized by a localized accumulation of subretinal fluid and an idiopathic focal leakage from choroidal vessels. The exact pathogenesis of CSC, however, still remains obscure. In this paper, we hypothesized that CSC may result from a response of choroidal vessels to an acute increase in the environmental light intensity leading to a focal leakage from the choroidal vessels. High levels of glucocorticoids, in our proposed model, may cause persistence rather than initiation of the focal leakage, probably by suppressing the synthesis of collagen and extracellular matrix components and inhibiting fibroblastic activity. © 2016, International Journal of Ophthalmology (c/o Editorial Office). All rights reserved.

Item Type: Article
Additional Information: Cited By :3 Export Date: 16 February 2020 Correspondence Address: Norouzpour, A.; Eye Research Center, Khatam-Al-Anbia Eye Hospital, Gharani blvd, Iran; email: norouzpoura901@mums.ac.ir
Uncontrolled Keywords: Central serous chorioretinopathy Choroidal vessels Glucocorticoids Light intensity Temperature
Subjects: QU Biochemistry
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 01 Mar 2020 05:50
Last Modified: 01 Mar 2020 05:50
URI: http://eprints.mums.ac.ir/id/eprint/13128

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