A Complicated Course of Acute Viral Induced Pharyngitis, Icteric Hepatitis, Acalculous Cholecystitis, and Skin Rash

Sheybani, F. and Naderi, H. and Erfani, S. S. and Gharib, M. (2016) A Complicated Course of Acute Viral Induced Pharyngitis, Icteric Hepatitis, Acalculous Cholecystitis, and Skin Rash. Case Reports in Medicine, 2016.

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Abstract

This case reveals the complexities and challenges in the diagnosis of acute Epstein-Barr virus (EBV) infection, indicating the potential relationship between EBV infection and severe icteric hepatitis, acalculous cholecystitis, and lymphocytic vasculitis. We suggest including EBV infectious mononucleosis in the list of differential diagnoses when any of these clinical syndromes (or a combination thereof) occurs without apparent cause, especially in the presence of lymphocytosis. To our knowledge, this is the first report to suggest the possible role of EBV in the pathogenesis of cutaneous lymphocytic vasculitis. Also it is possible that EBV infection triggered the flare-up of the underlying rheumatologic disease. Therefore, it could be assumed that a part of the clinical syndrome (e.g., dermatologic manifestations) might be related to the flare-up of the underlying rheumatologic disease. © 2016 Fereshte Sheybani et al.

Item Type: Article
Additional Information: Cited By :1 Export Date: 16 February 2020 Correspondence Address: Gharib, M.; Department of Pathology, Faculty of Medicine, Mashhad University of Medical SciencesIran; email: gharibm@mums.ac.ir
Uncontrolled Keywords: alanine aminotransferase alkaline phosphatase aspartate aminotransferase bilirubin bilirubin glucuronide cefixime gamma glutamyltransferase ganciclovir hepatitis A vaccine penicillin G prednisolone valganciclovir acalculous cholecystitis adult alanine aminotransferase blood level alkaline phosphatase blood level Article aspartate aminotransferase blood level bilirubin blood level case report drug dose reduction epigastric pain Epstein Barr virus infection erythrocyte sedimentation rate female follow up hematocrit hepatitis histopathology human leukocyte low drug dose lymphocyte count nausea neutrophil count pathogenesis pharyngitis polymorphonuclear cell rash urticaria vomiting young adult
Subjects: QW Microbiology and Immunology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 26 Feb 2020 10:03
Last Modified: 26 Feb 2020 10:03
URI: http://eprints.mums.ac.ir/id/eprint/13213

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