Acquired angioedema induced by risperidone

Talaei, A. and Rad, S. F. and Moghani, M. B. and Talaei, A. (2016) Acquired angioedema induced by risperidone. Iranian Journal of Psychiatry and Behavioral Sciences, 10 (1).

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Introduction: Angioedema is a serious reaction characterized by edema of the deep dermal and subcutaneous tissues. Case Presentation: A 38-year-old woman was admitted to Ibn-e-Sina psychiatric hospital (Mashhad, Iran) in 2010, with amphetamine-induced mood disorder with onset during intoxication. She began taking sodium valproate, and later, risperidone treatment was started. On the 9th day of risperidone treatment, drug-induced angioedema occurred. Laboratory tests showed an elevated erythrocyte sedimentation rate and elevated C-reactive protein, with normal C3, C4, and C1 esterase inhibitor concentrations. Conclusions: The risperidone treatment was discontinued, and only hydroxyzine and a low dose of hydrocortisone were prescribed. The edema resolved completely within 4 days. © 2016, Mazandaran University of Medical Sciences.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Rad, S.F.; Psychiatry and Behavioral Sciences Research Center, Ibn-e-Sina Psychiatric HospitalIran; email:
Uncontrolled Keywords: Angioedema Risperidone Side effect amphetamine C reactive protein hydrocortisone hydroxyzine valproic acid adult aggression angioneurotic edema Article case report complement system corticosteroid therapy drug dependence drug dose increase drug withdrawal erythrocyte sedimentation rate face edema female grandiose delusion human irritability laboratory test logorrhea low drug dose mental hospital mood disorder neurologic examination periorbital edema physical examination protein blood level psychopharmacotherapy unemployment
Subjects: WG Cardiovascular System
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 26 Feb 2020 09:21
Last Modified: 26 Feb 2020 09:21

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