Comparing serum follicle-stimulating hormone (FSH) level with vaginal PH in women with menopausal symptoms

Vahidroodsari, F. and Ayati, S. and Yousefi, Z. and Saeed, S. (2010) Comparing serum follicle-stimulating hormone (FSH) level with vaginal PH in women with menopausal symptoms. Oman Medical Journal, 25 (1). pp. 13-16.

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Objectives: Despite the important implication for women’s health and reproduction, very few studies have focused on vaginal PH for menopausal diagnosis. Recent studies have suggested vaginal PH as a simple, noninvasive and inexpensive method for this purpose. The aim of this study is to compare serum FSH level with vaginal PH in menopause. Methods: This is a cross-sectional, descriptive study, conducted on 103 women (aged 31-95 yrs) with menopausal symptoms who were referred to the Menopausal Clinic at Ghaem Hospital during 2006. Vaginal pH was measured using pH meter strips and serum FSH levels were measured using immunoassay methods. The data was analyzed using SPSS software (version 11.5) and results were evaluated statistically by the Chi-square and Kappa tests. p≤0.05 was considered statistically significant. Results: According to this study, in the absence of vaginal infection, the average vaginal pH in these 103 menopausal women was 5.33 ±0.53. If the menopausal hallmark was considered as vaginal pH>4.5, and serum FSH as ≥20 mIU/ml, then the sensitivity of vaginal pH for menopausal diagnosis was 97. The mean of FSH levels in this population was 80.79 mIU/ml. Conclusion: Vaginal pH is a simple, accurate, and cost effective tool that can be suggested as a suitable alternative to serum FSH measurement for the diagnosis of menopause. © 2010, Oman Medical Specialty Board. All rights reserved.

Item Type: Article
Additional Information: Cited By :5 Export Date: 16 February 2020 Correspondence Address: Ayati, S.; Department of Obstetrics and Gynecology, Ghaem Hospital, Women’s Health Research Center, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: accuracy adult aged amenorrhea Article body mass comparative study cost effectiveness analysis cross-sectional study descriptive research family history female follitropin blood level human immunoassay major clinical study menopause questionnaire receiver operating characteristic reproduction vagina pH vaginitis women's health
Subjects: WQ Obstetrics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib4 lib4
Date Deposited: 04 Mar 2020 04:46
Last Modified: 04 Mar 2020 04:46

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