Relationship between menstruation regularity with total testosterone and ultrasonographic findings among hirsute women

Hajmolarezaei, Ezat and Ebrahimi, Mahbod and Moradi, Behnaz and Seddigh, Leila and Ghandi, Narges (2020) Relationship between menstruation regularity with total testosterone and ultrasonographic findings among hirsute women. The Iranian Journal of Obstetrics, Gynecology and Infertility, 22 (11). pp. 22-28.

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Abstract

Introduction: Regarding to the prevalence of polycystic ovarian syndrome and its complication in women at reproductive age, this study was performed with aim to evaluate the relationship between total testosterone and sonographic findings in two groups of married hirsute women with normal and oligomenohrric mensturation in order to find it as a predictor and diagnostic factor to replace with current methods. Methods: This case control study was performed on 93 hirsute patients in two groups of normal and oligomennohric menstruation in 2017-2018. Ferriman-Gallwey checklist was completed after clinical examination by gynecologist and then the patients were evaluated by vaginal ultrasonography and serum testosterone test. Data were analyzed by SPSS software (version 22) and t-test, Chi-square, Correlation, and regression tests. P<0.05 was considered statistically significant. Results: The level of total was 0.02- 2.8 nmol/lit, the mean of testosterone in regular menstruation group was 0.85 and in irregular menstruation group was 1.52. In regular menstrual hirsute group, there was significant relationship between hirsutism score in lower abdominal and thigh, and in irregular menstruation group, in lower abdominal and thigh and arm (p<0.05). In oligomennohric group, direct linear significant relationship was found between Gallwey score and sonographic findings (p<0.05). In addition, every quantified sonographic markers were checked with age, finally reverse linear relationship was found between mean number of follicles< 6 mm and age which indicates that the number of follicles< 6 mm will decrease with increasing age (p=0.01) Conclusion: In both groups, the relationship between total testosterone and lower abdominal, thigh and arm hair growth is clear that can be as a predictor factor for total testosterone level. However the sonographic findings are as predictor factor in irregular mensturation patients group.

Item Type: Article
Uncontrolled Keywords: Hirsutism,Menstruation,total Testosterone
Subjects: WP Gynecology
WQ Obstetrics
Divisions: Journals > Iranian J Obstetrics, Gynecology and Infertility
Depositing User: ijogi ijogi
Date Deposited: 22 Feb 2020 09:28
Last Modified: 22 Feb 2020 09:28
URI: http://eprints.mums.ac.ir/id/eprint/13321

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