Hepatoprotective activity of Mammea africana ethanol stem bark extract

Okokon, Jude Efiom and Burata Bawo, Michael and Orji Mbagwu, Herbert (2016) Hepatoprotective activity of Mammea africana ethanol stem bark extract. Avicenna Journal of Phytomedicine, 6 (2). pp. 248-259.

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Abstract

Mammea africana Sabine (Guttiferae) stembark, a common plant, traditionally used to treat various diseases and ailments was evaluated for hepatoprotective potentials against paracetamol- induced liver injury in rats. The hepatoprotective effect of the stembark extract (30-90 mg/kg) was evaluated by the assay of liver function parameters: total and direct bilirubin, serum protein and albumin, total cholesterol, alanine aminotransaminase (ALT), aspartate aminotransaminase (AST), and alkaline phosphatase activities (ALP), antioxidant enzymes: superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and histopathological study of the liver. The administration of the stembark extract caused significant (p

Item Type: Article
Subjects: W General medicine- Health professions
Divisions: Journals > Avicenna J Phytomedicine
Depositing User: ajp ajp
Date Deposited: 20 Sep 2017 12:49
Last Modified: 20 Sep 2017 12:49
URI: http://eprints.mums.ac.ir/id/eprint/1475

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