An Investigation of the Effects of Aerobic Exercise on Serum Brain Natriuretic Peptide and C-Reactive Protein in women with Cardiovascular Diseases

Sheykhiyan, Najmeh and Rahami, Eskandar and Ostovan, Mohammad ali (2015) An Investigation of the Effects of Aerobic Exercise on Serum Brain Natriuretic Peptide and C-Reactive Protein in women with Cardiovascular Diseases. Journal of Cardio-Thoracic Medicine, 3 (4). pp. 379-383.

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Abstract

Introduction: The aim of this study was to evaluate the effects of aerobic exercise on brain natriuretic peptide (BNP) and C-reactive protein (CRP) levels in women with cardiovascular diseases. Materials and Methods: In this semi experimental study, thirty female patients with at least one coronary artery stenosis (more than70) were chosen and divided into two groups of aerobic training (n=15) and control (n=15). Blood samples were obtained at the beginning and end of the study to measure brain natriuretic peptide (BNP) and C-reactive protein (CRP) levels. The aerobic group cycled on a stationary ergometer for three sessions per week (period of eight weeks). The control group did not receive any exercise. Each exercise session included a10-minute warm-up, a 15-minute or more aerobic training program and a 5-minute cool-down. In the warm-up and cool-down stages, running, walking and stretching activities were used. During the first week of training, subjects exercised for 15 minutes at 55-60 of their target heart rates. Each week, exercise duration extended by five minutes, while the intensity was unchanged. Results: Results indicated that 8 weeks of aerobic training had a significant effect on decreasing the BNP and CRP levels in females with Cardiovascular Diseases (P=0.005 and P=0.017 , respectively). Moreover, a significant Difference was seen between the control and experimental groups in mean BNP and CRP values (P=0.0001 and P=0.001 respectively), while no significant difference were seen between the pre and post tests in the Control group for BNP (P=0.21) and CRP (P= 0.28). There were significant reduction in BNP (pConclusion: Aerobic exercise can attenuate BNP and CRP levels in females with cardiovascular diseases; hence it can be used as a part of treatment.

Item Type: Article
Subjects: WG Cardiovascular System
Divisions: Journals > J Cardio-Thoracic Medicine
Depositing User: jctm jctm
Date Deposited: 20 Sep 2017 13:28
Last Modified: 20 Sep 2017 13:28
URI: http://eprints.mums.ac.ir/id/eprint/1567

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