Evaluation of the Efficacy of Standardized Uptake Value (SUV)-shape Scheme for Thyroid Volume Determination in Graves’ Disease: A Comparison with Ultrasonography

chen, yangchun and Xie, SiPei and He, Fang and Chen, JianWei (2017) Evaluation of the Efficacy of Standardized Uptake Value (SUV)-shape Scheme for Thyroid Volume Determination in Graves’ Disease: A Comparison with Ultrasonography. Asia Oceania Journal of Nuclear Medicine and Biology, 5 (1). pp. 44-48.

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Abstract

Objective(s): In this study, we aimed to evaluate the efficacy of thyroid volume measurement using 99mTc pertechnetate single-photon emission computed tomography (SPECT) images, acquired by the standardized uptake value (SUV)-shape scheme designed by our expert team.Methods: A total of 18 consecutive patients with Graves’ disease (GD) were subjected to both ultrasonographic and 99mTc pertechnetate SPECT examinations of thyroid within a five-day interval. The volume of thyroid lobes and isthmus was measured by ultrasonography (US) according to the ellipsoid volume equation. The total thyroid volume, determined as the sum of the volume of both lobes and isthmus, was recorded as TV-US (i.e., thyroid volume measured by US) and set as the reference. The thyroid volume was defined according to our SUV-shape scheme and was recorded as TV-SS (i.e., thyroid volume determined by the SUV-shape scheme). The data were analyzed using the Bland-Altman plot, linear regression analysis, Spearman’s rank correlation, and paired t-test, if necessary.Results: The values of TV-SS (40.2±29.4 mL) and TV-US (43.0±34.7 mL) were not significantly different (t=0.813; P=0.43). The linear regression equation of the two values was determined as TV-US= 1.072 × TV-SS − 0.29(r=0.906; P<0.01).Conclusion: The new scheme, i.e., SUV-shape scheme, exhibited potential for the measurement of thyroid volume in patients with GD.

Item Type: Article
Subjects: WN Radiology . Diagnostic Imaging
Divisions: Journals > Asia Oceania J Nuclear Medicine & Biology
Depositing User: AOJNMB AOJNMB
Date Deposited: 20 Sep 2017 13:35
Last Modified: 20 Sep 2017 13:35
URI: http://eprints.mums.ac.ir/id/eprint/1598

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