Long-term Results of Osteoarticular Allograft Reconstruction in Children with Distal Femoral Bone Tumors

Jamshidi, Khodamorad and Bahrabadi, Mehrdad and Mirzaei, Alireza (2017) Long-term Results of Osteoarticular Allograft Reconstruction in Children with Distal Femoral Bone Tumors. The Archives of Bone and Joint Surgery, 5 (5). pp. 296-301.

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Background: There is no consensus regarding the best method of reconstruction in pediatric population following thewide resection of malignant bone tumors. More exploration of the complications of osteoarticular reconstruction leads toless existing controversy of this type of reconstruction, which is the main point of this article.Methods: Long-term outcomes and complications of osteoarticular allograft reconstruction of primary distal femoral bonesarcomas in 22 children with mean age of 10.7 years old were reviewed in this study. Musculoskeletal Tumor Society(MSTS) scoring system was used for functional evaluation of the allografts.Results: With an average follow-up time of 81 months, the outcomes of 16 patients with allografts at the final follow upwere evaluated. As expected, Limb length discrepancy (LLD) was observed in all patients (mean LLD= 2.73cm), whichwas significantly correlated to allograft survival time (P<0.001). Degenerative joint disease (DJD) was also seen in allpatients and its grade was also significantly correlated to allograft survival time (P<0.001). The mean MSTS-score was74 at the latest follow-up, ranging from 60 to 90. Five and 10 year survival rate of allografts were found to be 93.3and 62.2, respectively.Conclusion: Osteoarticular allograft reconstruction could result in several complications including DJD. Despite itsconsiderable biologic advantage over endoprosthesis, osteoarticular allograft reconstruction is a long-lasting but still atemporary solution before performing megaprosthesis. This allows patients to preserve their remaining physis for limbgrowth and become old enough for an adult megaprosthesis.

Item Type: Article
Subjects: WE Musculoskeletal system
WO Surgery
Divisions: Journals > Archives of Bone & Joint Surgery
Depositing User: abjs abjs
Date Deposited: 20 Sep 2017 13:48
Last Modified: 20 Sep 2017 13:48
URI: http://eprints.mums.ac.ir/id/eprint/1637

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