Frequency of borrelia in morphea lesion by polymerase chain reaction in northeast of Iran

Yazdanpanah, M. J. and Sharifi, N. and Khooei, A. and Banihashemi, M. and Khaje-Daluee, M. and Shamsi, A. and Ghazvini, K. (2015) Frequency of borrelia in morphea lesion by polymerase chain reaction in northeast of Iran. Jundishapur Journal of Microbiology, 8 (8).

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Abstract

Background: The etiology of morphea is still unknown. Borrelia spp. as a causative agent of morphea has been discussed since 1985, but the relationship remains uncertain. Objectives: We aimed to find the frequency of Borrelia in morphea lesions by polymerase chain reaction (PCR) in northeast of Iran. Patients and Methods: Sixty six patients with morphea were prospectively included in the present study. For each patient, formalin-fixed, paraffin-embedded tissue blocks of skin lesion biopsies were examined for Borrelia spp. DNA using PCR. Results: No Borrelia DNA was detected by PCR in skin lesions of patients with morphea. Conclusions: The result of this study showed no relationship between Borrelia infection and morphea lesions and in other word indicated that morphea, at least in Iran, is not caused by Borrelia spp. © 2015, Ahvaz Jundishapur University of Medical Sciences.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Ghazvini, K.; Antimicrobial Resistance Research Center, Department of Microbiology and Virology, Mashhad University of Medical SciencesIran
Uncontrolled Keywords: Borrelia spp Morphea Polymerase chain reaction DNA formaldehyde paraffin adult aged Article Borrelia Borrelia infection case study child controlled study DNA determination female human human tissue Iran major clinical study male morbidity nonhuman preschool child prospective study skin biopsy
Subjects: WC Communicable Diseases
WR Dermatology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 26 Apr 2020 05:44
Last Modified: 26 Apr 2020 05:44
URI: http://eprints.mums.ac.ir/id/eprint/16472

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