Comparison of the level of sensory blockage in spinal anesthesia with bupivacaine 0.5 and lidocaine 5 in surgical patients

Pouryaghobi, S. M. and Ahmadinejad, M. and Mashak, B. and Ebrahimi, M. and Bolvardi, E. and Hashemian, A. M. and Ahmadi, K. (2015) Comparison of the level of sensory blockage in spinal anesthesia with bupivacaine 0.5 and lidocaine 5 in surgical patients. Biomedical and Pharmacology Journal, 8 (2). pp. 869-874.

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Spinal anesthesia is commonly done using lidocaine 5 and bupivacaine 0/5 in various surgeries. This method is accompanied with many complications including spreading anesthetic level to areas higher than that of local injection site. The aim of this study was to determine the spread of sensory block level in spinal anesthesia by using oflidocaine 5 and bupivacaine 0/5 in surgical patients. In a randomized clinical trial, 300 male and female patients who had undergone surgery by spinal anesthesia were randomly divided into two groups (lidocaine 5 and bupivacaine 0/5). After spinal anesthesia, the sensory block levels were checked every 5 minutes by the way of pin prick test and the results were recorded in a checklist. Data were analyzed using SPSS software. The highest anesthetic level in lidocaine 5 and bupivacaine 0/5 groups was C2 with 0.7 and C5 with 0.7 of cases respectively (p> 0/05). The mean times of getting to the highest sensory block level in lidocaine 5 and bupivacaine 0/5 groups were 11.53 minutes (+/-6.24) and 11.87 minutes ( +/-5.54) respectively after spinal anesthesia (p> 0.05). Anesthetic spreading to C1-C7 and T1-T4 dermatoms in lidocaine 5 group was accomplished in 1.3 and 10 of cases, and it was also reported for the same dermatoms in bupivacaine group 0.7 and 8 of cases respectively (p <0.05). Spinal anesthesia with bupivacaine 0/5 had lower sensory block distribution as compared to lidocaine 5, and it had lower complications compared to lidocaine5. Therefore, in order to obtain the desirable sensory block level, the use of bupivacaine 0/5 is recommended.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Ahmadi, K.; Department of Emergency Medicine, Alborz University of Medical SciencesIran; email:
Uncontrolled Keywords: Bupivacaine 0/5 Lidocaine 5 Sensory block level Spinal anesthesia bupivacaine lidocaine adult anesthesia level Article checklist controlled study female human major clinical study male pinprick test randomized controlled trial spine surgery surgical patient
Subjects: WO Surgery
QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 26 Apr 2020 06:37
Last Modified: 26 Apr 2020 06:37

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