Optimization of diazinon biodegradation from aqueous solutions by Saccharomyces cerevisiae using response surface methodology

Ehrampoush, M. H. and Sadeghi, A. and Ghaneian, M. T. and Bonyadi, Z. (2017) Optimization of diazinon biodegradation from aqueous solutions by Saccharomyces cerevisiae using response surface methodology. AMB Express, 7 (1).

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Abstract

Diazinon is an organophosphate compound that inhibits the activity of acetylcholinesterase. Standards of the World Health Organization and Environmental Protection Agency for diazinon concentration in water are 0.1 and 9 × 10−6 mg/L, respectively. The aim of this study was the optimization of diazinon biodegradation from aqueous solutions by Saccharomyces cerevisiae using the response surface methodology (RSM). Harvested cells of S. cerevisiae were locally purchased from the Iranian Research Organization for Science and Technology. To obtain the optimum condition for diazinon biodegradation using RSM, input parameters included the initial concentration of diazinon (0.01–10 mg/L), concentration of S. cerevisiae (0.5–5), pH (4–10), and retention time (1–30 h). The research study had a central composite design where one of the methods was RSM. According to the results, the observed values of the removal efficiency of diazinon were variable in the range of 23–96. The highest removal rate was obtained as 96 under the initial diazinon concentration of 2.5 mg/L, S. cerevisiae concentration of 3.88, pH of 5.5, and retention time of 22.75 h. The results displayed that the removal efficiency of diazinon had a direct relationship with the concentration of S. cerevisiae and retention time, and an inverse relationship with pH and the initial concentration of diazinon. We can conclude that S. cerevisiae has the ability to remove diazinon with the lowest cost and a high efficiency. © 2017, The Author(s).

Item Type: Article
Additional Information: Cited By :13 Export Date: 16 February 2020 Correspondence Address: Bonyadi, Z.; Department of Environmental Health Engineering, Environmental Science and Technology Research Center, Shahid Sadoughi University of Medical ScienceIran; email: zyabonyadi@yahoo.com
Uncontrolled Keywords: Biodegradation Diazinon RSM Saccharomyces cerevisiae dimpylate aqueous solution Article concentration (parameters) microbial degradation nonhuman process optimization response surface method retention time reversed phase high performance liquid chromatography
Subjects: QU Biochemistry
QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib3 lib3
Date Deposited: 12 May 2020 08:02
Last Modified: 12 May 2020 08:02
URI: http://eprints.mums.ac.ir/id/eprint/16804

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