Prevalence of the metabolic syndrome in kidney transplant recipients: A single-center study

Hami, M. and Sabbagh, M. G. and Sefidgaran, A. and Mojahedi, M. J. (2017) Prevalence of the metabolic syndrome in kidney transplant recipients: A single-center study. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 28 (2). pp. 362-367.

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Abstract

Metabolic syndrome (MS) is characterized by a combination of cardiovascular (CV) risk factors (hypertension, dyslipidemia, obesity, and alterations in glucose homeostasis). Insulin resistance is suggested to be the common pathogenic background. This syndrome is also a risk factor for diabetes and chronic kidney disease. In renal transplant recipients, MS has been shown to be an independent risk factor for chronic allograft dysfunction, graft failure, new-onset diabetes, and CV disease. We performed a cross-sectional study on 106 stable renal transplant recipients to detect MS between January 2013 and August 2013. This syndrome was diagnosed according to the National Cholesterol Education Program-Adult Treatment Panel III criteria. Patients with history of diabetes mellitus were excluded from the study. In this group of patients, 56 (52.8) had MS. There were 32 males (57.1) and 24 females (42.9). The mean age of the MS group was significantly higher than the non-MS group. The mean serum creatinine was higher in the MS group than the non-MS group, but there was no significant difference between them (P >0.05). The calculated glomerular filtration rate was also similar in the two groups (P >0.05). The patients with MS had higher body weight (64.61 ± 14.17 kg vs. 58.76 ± 11.70 kg, P <0.05) and also higher body mass index (BMI) (P <0.05). The prevalence of BMI >25 kg/m2 in the MS group was 75 versus 25 in the non-MS group (P <0.05). Since MS is an important and common risk factor in renal transplant recipients, we have to try to prevent it by educating the patients to control it by modifying their lifestyle. Efforts toward promoting healthy diets, physical activity, and blood pressure control must be undertaken.

Item Type: Article
Additional Information: Cited By :3 Export Date: 16 February 2020
Uncontrolled Keywords: adult body mass body weight cross-sectional study female glomerulus filtration rate graft recipient graft survival human Iran kidney kidney transplantation male metabolic syndrome X middle aged pathophysiology prevalence risk assessment risk factor surgery treatment outcome young adult Body Mass Index Cross-Sectional Studies Glomerular Filtration Rate Humans Metabolic Syndrome Risk Factors Transplant Recipients
Subjects: WJ Urogenital System
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib3 lib3
Date Deposited: 29 Apr 2020 06:40
Last Modified: 29 Apr 2020 06:40
URI: http://eprints.mums.ac.ir/id/eprint/16840

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