Antioxidant activities of Juniperus foetidissima essential oils against several oxidative systems

Emami, S. A. and Asgary, S. and Naderi, G. A. and Shams Ardekani, M. R. and Kasher, T. and Aslani, S. and Airin, A. and Sahebkar, A. (2011) Antioxidant activities of Juniperus foetidissima essential oils against several oxidative systems. Brazilian Journal of Pharmacognosy, 21 (4). pp. 627-634.

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Abstract

The present study aimed to evaluate the antioxidant activity of essential oils obtained from branchlets of male and female trees as well as fruits of Juniperus foetidissima Willd., Cupressaceae, from Iran. For this purpose,essential oils of J. foetidissima were phytochemically analyzed and different concentrations of them were tested in five oxidative systems: 1) low-density lipoprotein oxidation; 2) linoleic acid peroxidation; 3) red blood cell hemolysis; 4) hemoglobin glycation; and 5) insulin glycation assays. In all employed systems, antioxidant effects were observed from the three tested oils though in varying degrees. The most promising activities of the oils were observed against hemoglobin and insulin glycation. Antioxidant activities of the oilsdid not appear to be dose-dependent. In addition, no consistent superiority in antioxidant effects was observed from a single oil in different assays. In view of the current results, J. foetidissima branchlet and fruit oils could be regarded as effective natural products with anti-glycation activity.

Item Type: Article
Additional Information: Cited By :16 Export Date: 16 February 2020 Correspondence Address: Emami, S. A.; Department of Pharmacognosy, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran; email: emamia@mums.ac.ir
Uncontrolled Keywords: Anti-glycation Antioxidant Cupressaceae Essential oil Juniperus foetidissima alpha thujene apha cubebene beta pinene cedrol delta 2 carene e caryophyllene e thujone gamma cadinene germacrene D hemoglobin humulene insulin isoterpinolene Juniperus foetidissima extract limonene linoleic acid low density lipoprotein monoterpene hydrocarbon pinene plant extract sabinene sesquiterpene hydrocarbon terpene derivative terpinen 4 ol terpinene unclassified drug antioxidant activity article concentration response controlled study fruit glycation hemolysis human human cell Iran Juniperus lipid oxidation lipid peroxidation plant stem
Subjects: QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 19 Apr 2020 05:45
Last Modified: 19 Apr 2020 05:45
URI: http://eprints.mums.ac.ir/id/eprint/16964

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