Clinical and histopathological analysis of oral squamous cell carcinoma of young patients in Mashhad, Iran: A retrospective study and review of literatures

Falaki, F. and Dalirsani, Z. and Pakfetrat, A. and Falaki, A. and Saghravanian, N. and Nosratzehi, T. and Pazouki, M. (2011) Clinical and histopathological analysis of oral squamous cell carcinoma of young patients in Mashhad, Iran: A retrospective study and review of literatures. Medicina Oral, Patologia Oral y Cirugia Bucal, 16 (4). e473-e477.

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Clinical and histopathological analysis of oral squamous cell carcinoma of young patients in Mashhad, Iran. A retrospective study and review of literatures.pdf

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Abstract

Objectives: Oral Squamous cell carcinoma (OSCC) is primarily a disease that mainly occurs in males in their sixth and seventh decades of life and is rare in young adults. Study Design: In this retrospective study, records of patients under the age of 40, with the diagnosis of OSCC in the Oral Medicine Department of Mashhad Dental Faculty during the past 13 years were analyzed. Their socioeconomic data, demographic, clinical and histopathological characteristics, risk factors, familial history were assessed and applicable studies and case reports in the literatures were reviewed. PCR (Polymerase chain reaction) analysis was also done for detection of human papilloma virus (HPV). Results: From 158 cases of OSCC diagnosed in our centre, 21 patients were younger than 40 years. Most of them were young men (12 cases). There was no significant risk factor in this group. The most common site of involvement was the tongue. The most common clinical presentation was exophytic lesion with ulcer. No HPV DNA was detected in these patients. Conclusion: Characteristics of OSCC in young patients are different from older age group. Major risk factors (smoking and alcohol consumption and HPV) were not etiologic factors for OSCC in young patients in our province. © Medicina Oral S. L.

Item Type: Article
Additional Information: Cited By :33 Export Date: 16 February 2020 Correspondence Address: Dalirsani, Z.; Dental Research Center, Mashhad University of Medical Sciences, Department of Oral Medicine of Mashhad Dental School, Vakilabad Blvd, 91735 Mashhad, Iran; email: zdalirsani@gmail.com
Uncontrolled Keywords: Iran Oral cancer Oral squamous cell carcinoma Retrospective study Risk factors Young patients adult clinical article demography family history female histopathology human male mouth carcinoma odontogenic tumor polymerase chain reaction review risk factor sex ratio socioeconomics squamous cell carcinoma tongue virus detection Wart virus Carcinoma, Squamous Cell Humans Mouth Neoplasms Retrospective Studies Young Adult
Subjects: QS Human Anatomy
QU Biochemistry
WU Dentistry. Oral surgery
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 22 Apr 2020 03:37
Last Modified: 22 Apr 2020 03:37
URI: http://eprints.mums.ac.ir/id/eprint/16971

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