Accuracy of fine needle aspiration (FNA) in diagnosis of major salivary gland tumors

Madani, S. Z. and Naderi, N. J. and Merati, M. and Haghshenas, H. and Ashouri, M. (2011) Accuracy of fine needle aspiration (FNA) in diagnosis of major salivary gland tumors. Research Journal of Medical Sciences, 5 (2). pp. 99-101.

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Abstract

Salivary glands tumors consist a major part of human tumors which their differentiation and treatment are very different. In addition to clinical experiments, biopsy is helpful method to obtain an accurate diagnosis. The biopsy of oral lesions is provided in different ways and one of them is Fine Needle Aspiration (FNA) which is a non-invasive, easy, quick and low cost experiment. The aim of this study was to define the accuracy of FNA in identifying major salivary glands tumors. The study was descriptive, retrospective. The medical records of Department of Pathology, Amir Alam Hospital were reviewed from 1994-2004. Data including age, gender, lesion site and FNA reports of all cases were registered. Histopathologic results of FNA samples and surgical gross reports were matched. Descriptive data was used for registered data analyzing. The SPSS 11.5 software was used for statistical analysis. From 656 specimen of FNA, there were 235 cases with both results of FNA and excisional biopsy. About 55 cases in gross experiment had not been shown tumor like lesion and 11 cases in FNA had not a definite diagnosis because of non sufficient of specimen; all these cases were rejected from study. Next study was for other 169 specimen. Considering negative for benign and positive for malignant, 37, 104, 10 and 18 cases were true positive, true negative, false positive and false negative, respectively. Sensitivity, specificity and accuracy were obtained about 67, 91 and 83, respectively. Positive Predictive Value (PPV) and Negative Predictive Value (NPV) also were computed 78 and 85, respectively. FNA is a safe, useful and quick method for identifying tumors of major salivary glands.©Medwell Journals,2011.

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 Correspondence Address: Jalayernaderi, N.; Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Shahed University, Tehran, Iran
Uncontrolled Keywords: Accuracy Fine needle aspiration (FNA) Iran Major salivary glands tumors Sensitivity Specificity adolescent adult age aged article aspiration biopsy child computer program controlled study data analysis descriptive research diagnostic test accuracy study diagnostic value female gender histopathology human major clinical study male medical record review predictive value preschool child retrospective study salivary gland tumor sampling school child sensitivity and specificity tumor diagnosis
Subjects: WK Endocrine System
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 18 Apr 2020 07:28
Last Modified: 18 Apr 2020 07:28
URI: http://eprints.mums.ac.ir/id/eprint/17046

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