Iron balance in regular blood donors

Mozaheb, Z. and Khayami, M. and Sayadpoor, D. (2011) Iron balance in regular blood donors. Transfusion Medicine and Hemotherapy, 38 (3). pp. 190-194.

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Abstract

Background: Numerous reports have shown that iron stores decrease in blood donors after donation. As we need healthy donors, it is essential to test hemoglobin and ferritin levels for preventing reduced of iron stores in donors. Methods: This study was conducted on 235 healthy men. The donors were divided into three groups: group I) control group with no donation; group II) case group 1 with two donations within 1 year; group III) case group 2 with three donations within 1 year. Results: The mean level of hemoglobin was 15.9 and 14.7 g/dl in the control group and in the case group, respectively (p < 0.0000). The mean level of serum ferritin in group I, II and III, was 108, 56 and 26 mg/l, respectively (p < 0.0000). When studying various stages of iron deficiency in donors, it could be shown that 58 of group III donors but only 1 of control group donors had a negative iron balance. Moreover, iron deficiency anemia was observed in 20 of group III donors. Conclusion: Just measuring the hemoglobin level is not sufficient for selecting donors. In addition, testing of the ferritin level and iron supplementation are recommended in regular donors with more than one donation per year. Copyright © 2011 S. Karger AG, Basel.

Item Type: Article
Additional Information: Cited By :13 Export Date: 16 February 2020 CODEN: TMHRC Correspondence Address: Mozaheb, Z.; Department of Hematology-Oncology, Mashhad University of Medical Science, Blood Transfusion Organization of MashhadIran; email: mozahebz@mums.ac.ir
Uncontrolled Keywords: Blood donation Ferritin Iron balance Iron deficiency hemoglobin adolescent adult aged article blood donor controlled study disease classification ferritin blood level hemoglobin blood level human iron deficiency anemia male normal human vitamin supplementation
Subjects: WB Practice of Medicine
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 30 Apr 2020 03:46
Last Modified: 30 Apr 2020 03:46
URI: http://eprints.mums.ac.ir/id/eprint/17074

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