Pistachio allergy-prevalence and in vitro cross-reactivity with other nuts

Noorbakhsh, R. and Mortazavi, S. A. and Sankian, M. and Shahidi, F. and Tehrani, M. and Azad, F. J. and Behmanesh, F. and Varasteh, A. (2011) Pistachio allergy-prevalence and in vitro cross-reactivity with other nuts. Allergology International, 60 (4). pp. 425-432.

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Abstract

Background: Tree nut allergy is characterized by a high frequency of life-threatening reactions and is typically lifelong persistent. Some people with a pistachio nut allergy, which is common in the pistachio rich area of Iran, develop a hypersensitivity to other tree nuts as well. The aim of this study was to investigate the prevalence of pistachio nut allergy in Iran, the major pistachio cultivation region in the world. The study also addressed the presence of allergenic cross-reactivity between pistachio and other nuts, including almond, peanut, and cashew in pistachio allergic patients. Methods: A survey was conducted to determine whether the prevalence of pistachio allergy is affected by exposure to this nut in pistachio cultivation regions, as well as possible cross-reactivity between pistachio and other nuts including cashew, almond, and peanut. Inhibition Western blot and inhibition ELISA studies were conducted to assess the presence of allergenic cross-reactivity between pistachio and the other tree nuts. Results: Our results revealed that the prevalence of pistachio allergy is twice as much in pistachio cultivation regions than other areas. Western blotting and inhibition ELISA presented high percentages of inhibition with pistachio and cashew, followed by almond and, to some degree, peanut which indicates different levels of allergenic cross-reactivity. Conclusions: The results indicate that exposure of people to pistachio significantly affects the prevalence of its allergic reactions. In addition, it was observed that, among pistachio allergic subjects, such exposure may affect the co-sensitivities with other nuts, including cashew and almond. The plant taxonomic classification of pistachio and other tree nuts does appear to predict allergenic cross-reactivity. © 2011 Japanese Society of Allergology.

Item Type: Article
Additional Information: Cited By :21 Export Date: 16 February 2020 CODEN: ALINF Correspondence Address: Varasteh, A.; Immunology Research Center, Bu-Ali Research Institute, Mashhad University of Medical Sciences, Mashhad, Iran; email: varasteha@mums.ac.ir
Uncontrolled Keywords: Almond Cashew Cross-reactivity Peanut Pistachio (Pistacia vera) immunoglobulin E adolescent adult article cashew nut child cross reaction enzyme linked immunosorbent assay female health survey human in vitro study Iran major clinical study male nut allergy pistachio pistachio nut allergy prevalence priority journal school child structured questionnaire Western blotting
Subjects: QW Microbiology and Immunology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 02 May 2020 04:20
Last Modified: 02 May 2020 04:20
URI: http://eprints.mums.ac.ir/id/eprint/17087

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