Herpesviruses at Human aggressive periodontitis sites

Radvar, M. and Arab, H. R. (2006) Herpesviruses at Human aggressive periodontitis sites. International Journal of Virology, 2 (1). pp. 7-13.

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The aim of present study was to evaluate the frequency of 3 members of herpes virus family in the subgingival plaque samples from periodontal pockets and healthy sites of an aggressive periodontitis population. Fifteen subjects with aggressive periodontitis took part in this study. Subgingival plaque samples were harvested from their 3 deepest pockets and 3 healthy sites and subjected to a nested Polymerase Chain Reaction (PCR) technique to detect Human Cyto-megallo Virus (HCMV), Epstein Barr virus 1 (EBV-1) and Herpes Simplex Virus 1 (HSV-1). Seven individuals revealed HCMV in their diseased sites while only 2 of these individuals revealed HCMV at their healthy sites too. Three individuals showed EBV-1 only at their diseased sites, while the remainig diseased sites and all healthy sites were negative for this virus. Finally, HSV-1 was found only at one of the diseased samples, but none of the healthy samples. Members of the Herpesvirus family might be recovered at periodontal sites. The prevalence of these viruses seems to be greater at diseased sites than healthy sites. Herpesviruses might be involved in the pathogenesis of periodontal disease. © 2006 Academic Journals Inc., USA.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Radvar, M.; Department of Periodontology, Mashhad Dental School and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Uncontrolled Keywords: Aggressive periodontitis EBV-1 HCMV HSV-1 PCR virus DNA adolescent adult article clinical article controlled study disease severity DNA extraction Epstein Barr virus female gel electrophoresis Herpes simplex virus 1 Herpes virus human Human cytomegalovirus male pathogenesis periodontal disease periodontitis polymerase chain reaction prevalence tissue distribution tooth plaque virus detection virus genome Herpesviridae Human herpesvirus 1 Human herpesvirus 4
Subjects: WC Communicable Diseases
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib7 lib7
Date Deposited: 29 Apr 2020 04:14
Last Modified: 29 Apr 2020 04:14
URI: http://eprints.mums.ac.ir/id/eprint/17094

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