Risk of obstructive sleep apnea and hemodialysis efficacy

Amini, M. and Roohafza, F. and Nazemian, F. and Morovatdar, N. and Hatefi Olaee, A. (2018) Risk of obstructive sleep apnea and hemodialysis efficacy. Journal of Nephropathology, 7 (3). pp. 201-206.

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Background: Obstructive sleep apnea (OSA) occurs frequently in hemodialysis (HD) patients with important consequences and increased mortality. However the role of adequacy of HD on the prevalence of OSA is less studied. Objectives: Our aim was to screen OSA and evaluate the effect of HD adequacy on the risk of OSA. Patients and Methods: This is a cross-sectional study on adult HD patients. Clinical and laboratory parameters were collected. The risk of OSA was assessed by STOP-BANG and Berlin questionnaire (BQ). Excessive daytime sleepiness (EDS) was evaluated with Epworth Sleepiness Scale (ESS). Kt/V index was applied for determining HD adequacy. Mortality followed after 2 years. Results: Sixty-five patients (63 men, with a mean age of 53 ± 16.5 years) were included in the study. Most of the subjects were categorized as high risk by Berlin (68.3) and STOP-BANG (84.6) questionnaires and 25.8 had EDS. Participants who were categorized as high risk of OSA showed lower Kt/V (P = 0.018 based on BQ, P = 0.002 based on STOP-BANG). OSA risk was significantly correlated with Kt/V (OR: 0.007; CI: 0-0.36; p: 0.01). Two-year mortality was not significantly correlated with OSA. Conclusion: OSA was prevalent in our HD patients and correlated with less adequacy of HD. Screening for this common disease by nephrologists using simple questionnaires is recommended. © 2018 The Author(s).

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Hatefi Olaee, A.; Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical SciencesIran; email: hatefioa@mums.ac.ir
Uncontrolled Keywords: Berlin questionnaire Hemodialysis Obstructive sleep apnea STOP-BANG questionnaire parathyroid hormone adult anthropometric parameters Article body mass cholesterol level clinical evaluation cohort analysis controlled study correlation analysis daytime somnolence efficacy parameters Epworth sleepiness scale evaluation and follow up fatigue female glucose blood level hemoglobin determination human hypertension hypertrophy major clinical study male medical record middle aged mortality multivariate logistic regression analysis neck circumference nephrologist neurologic examination prevalence questionnaire retrospective study risk factor scoring system screening sleep disordered breathing snoring social welfare STOP BANG triacylglycerol blood level univariate analysis waist circumference young adult
Subjects: WF Respiratory System
WJ Urogenital System
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 09 Jun 2020 06:14
Last Modified: 09 Jun 2020 06:14
URI: http://eprints.mums.ac.ir/id/eprint/17189

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