Low back pain and paraplegia as initial clinical presenting of medulloblastoma: A case report

Anvari, K. and Dehghan, P. and Ehsaee, M. R. and Bahadorkhan, G. (2018) Low back pain and paraplegia as initial clinical presenting of medulloblastoma: A case report. International Journal of Cancer Management, 11 (3).

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Introduction: Medulloblastoma is one of the most common malignancies in children. Common clinical symptoms of patients are related to the symptoms due to tumor in the posterior cranial fossa. Presentation of patients with symptoms related to metastatic tumors in the spinal canal are unusual. Case Presentation: We present a 6-year-old child with symptoms of lower back pain and Paraplegia as early symptoms of medulloblastom. The Magnetic Resonance Image (MRI) of spinal cord revealed multiple tumors in the spinal canal (initially diagnosed). A biopsy of the tumor was also performed. Then, whole CNS (Central Nervous System) imaging revealed tumor in the posterior cranial fossa. He had a dramatic improvement after treatment and returned to normal in all clinical signs. Four years have passed from his treatment and he is symptom free. Conclusions: Presentation of Medulloblastoma with widespread spinal canal drop metastases is rare. However, spinal drop metastasis should be considered to prevent a suboptimal management in child. These patients did not consider in aspect of the treatment outcome as hopeless. © 2018, Cancer Research Center (CRC), Shahid Beheshti University of Medical Sciences.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Dehghan, P.; Torbat Heydariyeh University of Medical SciencesIran; email: pardehghan@yahoo.com
Uncontrolled Keywords: Drop metastasis Low back pain-paraplegia Medulloblastom carboplatin CD99 antigen cyclophosphamide Article biopsy cancer radiotherapy case report child clinical article feces incontinence human human tissue immunohistochemistry low back pain male medulloblastoma multiple cycle treatment nuclear magnetic resonance imaging paraplegia preschool child radiation dose spine tumor tendon reflex urine incontinence
Subjects: WE Musculoskeletal system
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 08 Jun 2020 05:46
Last Modified: 08 Jun 2020 05:46
URI: http://eprints.mums.ac.ir/id/eprint/17193

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