Assessment of accuracy of out-of-field dose calculations by TiGRT treatment planning system in radiotherapy

Bahreyni Toossi, M. and Soleymanifard, S. and Farhood, B. and Mohebbi, S. and Davenport, D. (2018) Assessment of accuracy of out-of-field dose calculations by TiGRT treatment planning system in radiotherapy. Journal of Cancer Research and Therapeutics, 14 (3). pp. 634-639.

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Aim: The objective was to quantify the accuracy of dose calculation for out-of-field regions by the commercially available TiGRT version 1.2 (LinaTech, Sunnyvale, CA, USA) treatment planning system (TPS) for a clinical treatment delivered on a Siemens Primus with the single energy of 6 MV. Materials and Methods: Two tangential open fields were planned by TiGRT TPS to irradiate the left breast of a RANDO phantom. Dose values to out-of-field points were calculated by TiGRT TPS. A RANDO phantom was then irradiated, and dose values at set points were measured using thermoluminescent detectors-100 (TLDs-100) which were located within the phantom. Finally, the TLD-measured dose was compared to the TPS-calculated dose and the accuracy of TPS calculations at different distances from the field edge was quantified. Results: The measurements showed that TiGRT TPS generally underestimated the dose of out-of-field points and this underestimation worsened for regions relatively close to the treatment field edge. The mean underestimation of out-of-field doses was 39. Nevertheless, the accuracy of dose calculation by this TPS for most in-field regions was within tolerance. Conclusion: This study highlights the limitations of TiGRT TPSs in calculating of the out-of-field dose. It should be noted that out-of-field data for this TPS should only be applied with a certain understanding of the accuracy of calculated dose outside the treatment field. Therefore, using the TPS-calculated dose could lead to an underestimation of secondary cancer risk as well as a weak clinical decision for patients with implantable cardiac pacemakers or pregnant patients. © 2017 Journal of Cancer Research and Therapeutics | Published by Wolters Kluwer - Medknow.

Item Type: Article
Additional Information: Cited By :9 Export Date: 16 February 2020 Correspondence Address: Bahreyni Toossi, M.; Department of Medical Physics Research Center, Faculty of Medicine, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: Dose calculation accuracy out-of-field TiGRT treatment planning system cobalt 60 Article breast radiotherapy cancer radiotherapy clinical assessment comparative study controlled study diagnostic accuracy dose calculation human measurement accuracy outcome assessment radiation dose thermoluminescence dosimetry treatment planning algorithm breast tumor female imaging phantom intensity modulated radiation therapy procedures radiotherapy dosage radiotherapy planning system standards Algorithms Breast Neoplasms Humans Phantoms, Imaging Radiotherapy Planning, Computer-Assisted Radiotherapy, Intensity-Modulated Thermoluminescent Dosimetry
Subjects: QT physiology
WN Radiology . Diagnostic Imaging
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 26 May 2020 08:13
Last Modified: 26 May 2020 08:13

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