Nosocomial pneumonia in patients admitted to the intensive care unit of a tertiary care center in Mashhad, northeast of Iran; an etiologic survey

Farid, G. A. and Moghaddam, A. B. and Bojdy, A. (2018) Nosocomial pneumonia in patients admitted to the intensive care unit of a tertiary care center in Mashhad, northeast of Iran; an etiologic survey. Archives of Clinical Infectious Diseases, 13 (4).

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Abstract

Background: Hospital-acquired pneumonia (HAP) prevalence is related to patients’ population and diagnostic methods. HAP incidence is reported in different studies from 9 to 46. The current study aimed at evaluating the etiology of HAP in patients admitted to intensive care units (ICUs). Methods: The patients admitted to ICU of Imam Reza hospital (a tertiary care and teaching hospital in Mashhad, Northeast of Iran) were evaluated for HAP based on the following criteria: fever, leukocytosis, purulent discharge, new radiologic findings, changes in O2 saturation, and ventilator setting. Blood and endotracheal aspirates cultures were performed for all patients. Demographic characteristics were recorded in a checklist. Results: Among the 88 adult patients enrolled in the current study, the most frequent radiologic finding was patchy infiltration in chest X-ray (71.6). Mean age of the patients was 58 ± 20.1 years; mean hospital stay was 63 ± 40.8 days; mean interval between hospitalization and pneumonia development was 20.9 ± 16.8 days; and 41 patients (46.6) died. Acinetobacter spp. were the most frequent microorganisms in purulent discharge and methicillin-resistant Staphylococcus aureus (MRSA) were the main bacteria isolated from blood culture. Conclusions: Early diagnosis and appropriate antibiotic therapy can decrease HAP mortality and morbidity. The current study findings revealed that Acinetobacter app. were the most frequent cause of HAP in ICU patients in the studied center, which should be considered at the time of diagnosis and empirical antibiotics administration. Appropriate infection control and preventive measures should also be taken in ICUs to prevent HAP, especially against those caused by Acinetobacter spp. © 2018, Archives of Clinical Infectious Diseases.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Bojdy, A.; Infection Control and Hand Hygine Research Center, Faculty of Medicine, Mashhad University of Medical SciencesIran; email: bojdya@mums.ac.ir
Uncontrolled Keywords: Hospital-acquired pneumonia Intensive care unit Nosocomial infection Nosocomial pneumonia Ventilator-associated pneumonia carbapenem Acinetobacter adult antibiotic therapy Article bacterium isolation blood culture blood oxygen tension clinical evaluation cohort analysis disease course early diagnosis female hospital acquired pneumonia human infection control Iran length of stay lung infiltrate major clinical study male methicillin resistant Staphylococcus aureus middle aged nonhuman pathogenicity teaching hospital tertiary care center thorax radiography tracheal aspiration procedure
Subjects: WC Communicable Diseases
WF Respiratory System
WY Nursing
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 20 May 2020 08:39
Last Modified: 20 May 2020 08:39
URI: http://eprints.mums.ac.ir/id/eprint/17276

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