Biosynthesis and cytotoxic activity of lead oxide nanoparticles

Miri, A. and Sarani, M. and Hashemzadeh, A. and Mardani, Z. and Darroudi, M. (2018) Biosynthesis and cytotoxic activity of lead oxide nanoparticles. Green Chemistry Letters and Reviews, 11 (4). pp. 567-572.

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Abstract

Lead oxide (PbO) is known as an important industrial material. It is a semiconductor that has two crystalline forms, litharge (tetragonal crystalline structure) and massicot (orthorhombic crystalline structure). In this research, lead oxide nanoparticles (PbO-NPs) have been synthesized through the utilization of gelatin as a stabilizer, while its cytotoxic effects were investigated on Neueo2A cancer cell line. The generation of PbO-NPs was confirmed by the UV-Vis spectroscopy, PXRD, TG-DTA, EDX, and FESEM. The results of diffraction patterns of synthesized nanoparticles show the formation of both form α-PbO-NPs (tetragonal) and β-PbO-NPs (orthorhombic). The particles size of synthesized PbO-NPs was calculated to be around 10–20 nm. The cytotoxic activity of the synthesized PbO-NPs indicated that concentrations under 30 μg/mL have insignificant toxicity. © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

Item Type: Article
Additional Information: Cited By :10 Export Date: 16 February 2020 Correspondence Address: Darroudi, M.; Nuclear Medicine Research Center, Mashhad University of Medical SciencesIran; email: darroudim@mums.ac.ir
Uncontrolled Keywords: Biosynthesis Cytotoxicity α-PbO-NPs β-PbO-NPs cancer cell organelle concentration (composition) lead nanoparticle particle size semiconductor industry toxicity
Subjects: QU Biochemistry
QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 09 May 2020 08:47
Last Modified: 09 May 2020 08:47
URI: http://eprints.mums.ac.ir/id/eprint/17400

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