Errors in diagnosis of infective endocarditis

Naderi, H. R. and Sheybani, F. and Erfani, S. S. (2018) Errors in diagnosis of infective endocarditis. Epidemiology and Infection, 146 (3). pp. 394-400.

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Infective endocarditis (IE) is now the third or fourth most common life-threatening infectious disease. The high morbidity and mortality rates in the absence of appropriate care necessitate a thorough understanding of the obstacles towards the early diagnosis and management of IE. The aim of this study was to evaluate the frequency of discrepancy in diagnosis (i.e. discrepancy between the reason for admission and discharge diagnosis) and associated factors in patients with IE. It was a retrospective review of hospital records of all adult patients admitted in a 1000-bed academic general hospital in Mashhad, Iran with the discharge diagnosis of IE. Discrepancy in diagnosis on admission was observed in 64 (54.2) of 118 episodes of IE. For patients with discrepant diagnosis, the odds of poor outcome were more than two times higher than the odds of those with the non-discrepant diagnosis. Multivariate analysis identified the only history of prosthetic valve replacement as an independent factor in predicting non-discrepant diagnosis. We suggest that in facing a patient with the complex clinical scenario, proposing a comprehensive clinical syndrome that includes predisposing factors instead of a symptom or finding-based diagnosis can help making the differential diagnosis more accurate. Copyright © 2018 Cambridge University Press.

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 CODEN: EPINE Correspondence Address: Sheybani, F.; Department of Infectious Diseases, Faculty of Medicine, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: Diagnostic error infective endocarditis adult aged Article bacterial endocarditis female general hospital hospital admission hospital discharge human Iran major clinical study male outcome assessment patient risk retrospective study risk factor endocarditis hospitalization middle aged statistics and numerical data very elderly young adult Aged, 80 and over Diagnostic Errors Humans Retrospective Studies
Subjects: WC Communicable Diseases
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 08 May 2020 15:08
Last Modified: 08 May 2020 15:08

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