Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors

Pour, N. H. and Farajollahi, A. and Jamali, M. and Zeinali, A. and Jangjou, A. G. (2018) Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors. Polish Journal of Medical Physics and Engineering, 24 (1). pp. 25-31.

[img] Text
Comparison of three and four-field radiotherapy technique and the effect of laryngeal shield on vocal and spinal cord radiation dose in radiotherapy of non-laryngeal head and neck tumors.pdf

Download (914kB)

Abstract

Introduction: Due to the effect of radiation on both the tumor and the surrounding normal tissues, the side effects of radiation in normal tissues are expected. One of the important complications in the head and neck radiotherapy is the doses reached to the larynx and spinal cord of patients with non-laryngeal head and neck tumors. Materials and Methods: In this study, CT scan images of 25 patients with non-laryngeal tumors including; lymph nodes, tongue, oropharynx and nasopharynx were used. A three-field and a four-field treatment planning with and without laryngeal shield in 3D CRT technique were planned for each patient. Subsequently, the values of Dmin, Dmean, Dmax and Dose Volume Histogram from the treatment planning system and NTCP values of spinal cord and larynx were calculated with BIOPLAN and MATLAB software for all patients. Results: Statistical results showed that mean values of doses of larynx in both three and four-field methods were significantly different between with and without shield groups. Comparison of absorbed dose didn't show any difference between the three and four field methods (P>0.05). Using Shield, just the mean and minimum doses of spinal cord decreased in both three and four fields. The NTCP of the spinal cord and larynx by three and four-field methods with shield in the LKB and EUD models significantly are less than that of the three and four fields without shields, and in the four-field method NTCP of larynx is less than three radiation field. Conclusion: The results of this study indicate that there is no significant difference in doses reached to larynx and spinal cord between the treatments techniques, but laryngeal shield reduce dose and NTCP values in larynx considerably. © 2018 Noushin Hassan Pour et al., published by De Gruyter Open.

Item Type: Article
Additional Information: Export Date: 16 February 2020
Uncontrolled Keywords: 3D CRT DVH larynx NTCP spinal cord Article cancer radiotherapy clinical article comparative effectiveness female four field radiotherapy head and neck tumor human larynx edema lymphoma male nasopharynx tumor oropharynx tumor radiation dose radiation field three field radiotherapy tongue tumor x-ray computed tomography
Subjects: WF Respiratory System
WN Radiology . Diagnostic Imaging
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 07 May 2020 06:26
Last Modified: 07 May 2020 06:26
URI: http://eprints.mums.ac.ir/id/eprint/17466

Actions (login required)

View Item View Item