Which common test should be used to assess spleenautotransplant effect?

Soltani, E. and Aliakbarian, M. and Ghaffarzadegan, K. (2018) Which common test should be used to assess spleenautotransplant effect? Ulusal Travma ve Acil Cerrahi Dergisi, 24 (1). pp. 16-19.

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BACKGROUND: Historically, total splenectomy was the only choice of treatment for traumatic splenic injuries. However, non-operative management and spleen-preserving surgical techniques are preferred in modern medicine. In some situations in which the surgeon has to perform splenectomy, spleen autotransplant may preserve the splenic function. Selecting the best method for evaluating the splenic autotransplant effect has been debated for several years. In this study, we compared three common tests in evaluating the implanted spleen function. METHODS: Participants included 10 patients who were candidates for laparotomy and splenectomy. After performing splenectomy, we implanted five pieces of the spleen in the greater omentum of each patient. After 3 months, the implanted spleen function was evaluated by nuclear red blood cell (RBC) scan, serum immunoglobulin (Ig) M level, and presence of Howell-Jolly (HJ) bodies in the peripheral blood smear. RESULTS: All patients had normal peripheral blood smear. The IgM level was lower than normal in one patient, and scintigraphy did not demonstrate the transplanted spleen in another patient. CONCLUSION: All these tests may have comparable results, but because of availability and low cost of peripheral blood smear, which is also easily performed, it can be considered as the first option to evaluate the implanted spleen function. © 2018 Turkish Association of Trauma and Emergency Surgery.

Item Type: Article
Additional Information: Cited By :1 Export Date: 16 February 2020 Correspondence Address: Aliakbarian, M.; Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical SciencesIran; email: aliakbarianm@mums.ac.ir
Uncontrolled Keywords: IgM level Nuclear red blood cell scan Spleen autotransplant Spleen function Splenectomy immunoglobulin M adolescent adult Article autotransplantation clinical article clinical assessment diagnostic procedure female human laparotomy male prospective study scintigraphy spleen spleen transplantation young adult abdominal injury erythrocyte inclusion body injuries metabolism omentum spleen rupture transplantation treatment outcome Abdominal Injuries Erythrocyte Inclusions Humans Splenic Rupture Transplantation, Autologous
Subjects: WH Hemic and Lymphatic System
WO Surgery
Divisions: Mashhad University of Medical Sciences
Depositing User: lib2 lib2 lib2
Date Deposited: 04 May 2020 04:31
Last Modified: 04 May 2020 04:31
URI: http://eprints.mums.ac.ir/id/eprint/17542

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