Oral midazolam for voiding dysfunction in children undergoing Voiding Cystourethrography: A controlled randomized clinical trial

Azarfar, A. and Esmaeeili, M. and Farrokh, A. and Alamdaran, A. and Keykhosravi, A. and Neamatshahi, M. and Hebrani, A. and Ravanshad, Y. (2014) Oral midazolam for voiding dysfunction in children undergoing Voiding Cystourethrography: A controlled randomized clinical trial. Nephro-Urology Monthly, 6 (3).

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Abstract

Background: Voiding Cystourethrography (VCUG) is the gold standard of detecting and grading the vesicoureteral reflux. Moreover, VCUG is a part of the standard review for infants and children with a urinary tract infection and urinary dysfunction. Objectives: The purpose of our study was to compare using oral midazolam in contrast to prescribing no sedative medication for voiding dysfunction in children undergoing VCUG. Patients and Methods: In a clinical trial, we studied 84 children referred for VCUG. Children were allocated randomly into two equal groups. The intervention group received 0.5 mg/kg midazolam orally half an hour before the VCUG procedure. Then both groups were compared using statistical methods. Results: Then both groups were compared using statistical methods. In more than half of the patients, the main cause of performing VCUG was urinary tract infection. Dysuria was evaluated immediately after VCUG and was more frequent in girls than in boys (P = 0.006). After one week, the urinary irritation and restlessness in the intervention group was significantly lower than the control group. Conclusion: The use of midazolam 0.5 mg/kg reduced children's stress and increased their cooperation during the procedure. © 2014, Nephrology and Urology Research Center.

Item Type: Article
Additional Information: Cited By :6 Export Date: 16 February 2020 Correspondence Address: Ravanshad, Y.; Education Development Center, Mashhad University of Medical Sciences, Mashhad, Iran; email: ravanshady@mums.ac.ir
Uncontrolled Keywords: Child Midazolam Voiding Cystourethrography article comparative effectiveness controlled study drug efficacy dysuria female human major clinical study male micturition cystourethrography micturition disorder prescription randomized controlled trial sex ratio stress incontinence treatment duration treatment response urinary frequency urinary irritation urinary restlessness urinary tract infection
Subjects: WN Radiology . Diagnostic Imaging
WS Pediatrics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib6 lib6
Date Deposited: 24 Oct 2020 06:42
Last Modified: 24 Oct 2020 06:42
URI: http://eprints.mums.ac.ir/id/eprint/17692

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