Evaluation of Plasma Soluble Human Leukocyte Antigen-G Level in Asthmatic Children Aged 2 to 14 Years Old in Ghaem Hospital

Heydarian, Farhad and Khalesi, Maryam and Golmakani, Hasan and Kazemi, Mohammad Reza and Karimi, Mohammad and Heidarian, Mohammad and Rahmani, Shaghayegh (2016) Evaluation of Plasma Soluble Human Leukocyte Antigen-G Level in Asthmatic Children Aged 2 to 14 Years Old in Ghaem Hospital. Journal of Patient Safety & Quality Improvement, 4 (3). pp. 410-411.

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Abstract

Introduction: To evaluate serum level of plasma soluble human leukocyte antigen-G (sHLA-G) in asthmatic children aged 2 to 14 years old. Materials and Methods: This prospective, cross-sectional study was conducted on 83 patients aged 2-14 years in Ghaem Hospital, Mashhad, Iran, during 2013-2015. The participants were divided into two groups of asthmatic patients (n=29) and healthy children (n=54). Blood samples were drawn from the case (on admission) and control groups. Results: In the control group, 33 cases were male (61.1) and 21 (38.9) were female. In the case group, 18 patients (62.1) were male and 11 (37.9) were female (P=0.65). Mean ages of the control and case groups were 4.75±3.57 and 4.93±2.38 years, respectively (P=0.17). Mean serum levels of sHLA-G in the control and case groups were 396.51±279 U/ml and 184.58±302.08 U/ml, respectively (P<0.001). Conclusion:Serum level of sHLA was significantly lower in the asthmatic children compared to healthy ones.

Item Type: Article
Subjects: WB Practice of Medicine
Divisions: Journals > J Patient Safety & Quality improvement
Depositing User: psj psj
Date Deposited: 20 Sep 2017 14:57
Last Modified: 20 Sep 2017 14:57
URI: http://eprints.mums.ac.ir/id/eprint/1795

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