Genetic and molecular bases of esophageal Cancer among Iranians: An update

Abbaszadegan, M. R. and Keyvani, V. and Moghbeli, M. (2019) Genetic and molecular bases of esophageal Cancer among Iranians: An update. Diagnostic Pathology, 14 (1).

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Background: Esophageal cancer is one of the leading causes of cancer related deaths among the Iranians. There is still a high ratio of mortality and low 5 years survival which are related to the late onset and diagnosis. Majority of patients refer for the treatment in advanced stages of tumor progression. Main body: It is required to define an efficient local panel of diagnostic and prognostic markers for the Iranians. Indeed such efficient specific panel of markers will pave the way to decrease the mortality rate and increase the 5 years survival among the Iranian patients via the early diagnosis and targeted therapy. Conclusion: in present review we have reported all of the molecular markers in different signaling pathways and cellular processes which have been assessed among the Iranian esophageal cancer patients until now. © 2019 The Author(s).

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Moghbeli, M.; Medical Genetics Research Center, Mashhad University of Medical SciencesIran; email:
Uncontrolled Keywords: Diagnosis Esophageal cancer Iran Panel marker Prognosis tumor marker esophageal squamous cell carcinoma esophagus tumor genetics human metabolism pathology Biomarkers, Tumor Esophageal Neoplasms Humans
Subjects: QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib1 lib1
Date Deposited: 21 Jun 2020 04:58
Last Modified: 21 Jun 2020 04:58

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