Distribution of iris color and its association with ocular diseases in a rural population of Iran

Hashemi, H. and Pakzad, R. and Yekta, A. and Shokrollahzadeh, F. and Ostadimoghaddam, H. and Mahboubipour, H. and Khabazkhoob, M. (2019) Distribution of iris color and its association with ocular diseases in a rural population of Iran. Journal of Current Ophthalmology, 31 (3). pp. 312-318.

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Abstract

Purpose: To determine the distribution of iris color and its relationship with some ocular diseases in a rural population of Iran. Methods: Two rural areas of the north and southwest of Iran were selected by a cross-sectional study using multi-stage cluster sampling. After selecting samples, the participants had an eye examination including measuring visual acuity, refraction, and Pentacam imaging. Then an eye examination for individuals was performed by slit-lamp. Results: Out of 3851 invited people, 3314 participated in this study (participation rate, 86.05). Dark brown 41.28%, confidence interval (CI) 95% = 31.88–50.68 and blue (0.99%, CI 95% = 0.57–1.41) were the most and the least type of iris colors among participants of this study. Compared to others, people with a dark iris have the biggest anterior chamber depth (ACD), angle and volume while central corneal thickness (CCT), keratometry and pupil were highest among people with a dark brown iris (P < 0.002). Considering the dark brown group as a base group, the chances of being afflicted to cataract among people with dark, light brown, green, and blue irises are 1.89 (CI 95% = 1.25–2.86), 1.53 (CI 95% = 1.17–2.01), 4.60 (CI 95% = 2.17–9.71), and 12.17 (CI 95% = 5.05–29.31), respectively. The chance of being afflicted to myopia among people with green irises and to hyperopia among people with blue irises were high (1.60, CI 95% = 1.08–2.36 and 3.20, CI 95% = 1.03–9.97, respectively). Conclusions: Dark brown was the most prevalent iris color in rural areas of Iran. The index of cornea among people with dark and dark brown iris color is higher than other people, and people with light iris color are at a higher risk of developing eye disease such as cataract, corneal opacity, and refractive error. To determine this relationship and its usage for therapeutic and public health purposes, further studies are recommended. © 2018 Iranian Society of Ophthalmology

Item Type: Article
Additional Information: Cited By :2 Export Date: 16 February 2020 Correspondence Address: Khabazkhoob, M.; Department of Medical Surgical Nursing, School of Nursing and Midwifery, ShahidBeheshti University of Medical SciencesIran; email: Khabazkhoob@yahoo.com
Uncontrolled Keywords: Cornea indices Iris color Ocular disease Population-based cross-sectional study adolescent adult aged Article central corneal thickness child circadian rhythm cluster analysis controlled study cornea opacity cross-sectional study disease association eye color eye disease eye examination female groups by age human hypermetropia Iran keratometry major clinical study male myopia rural population slit lamp microscopy visual acuity
Subjects: WW Ophthalmology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib1 lib1
Date Deposited: 21 Jun 2020 06:32
Last Modified: 21 Jun 2020 06:32
URI: http://eprints.mums.ac.ir/id/eprint/18396

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