Neuroprotective potency of some spice herbs, a literature review

Khazdair, M. R. and Anaeigoudari, A. and Hashemzehi, M. and Mohebbati, R. (2019) Neuroprotective potency of some spice herbs, a literature review. Journal of Traditional and Complementary Medicine, 9 (2). pp. 98-105.

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Abstract

In recent years, growing attention has been given to traditional medicine. In traditional medicine a large number of plants have been used to cure neurodegenerative diseases such as Alzheimer ’ s disease (AD) and other memory related disorders. Crocus sativus (C. sativus), Nigella sativa (N. sativa), Coriandrum sativum (C. sativum), Ferula assafoetida (F. assafoetida), Thymus vulgaris (T. vulgaris), Zataria multiflora (Z. multiflora) and Curcuma longa (C. longa) were used traditionally for dietary, food additive, spice and various medicinal purposes. The Major components of these herbs are carotenoids, monoterpenes and poly phenol compounds which enhanced the neural functions. These medicinal plants increased anti-oxidant, decreased oxidant levels and inhibited acetylcholinesterase activity in the neural system. Furthermore, neuroprotective of plants occur via reduced pro-inflammatory cytokines such as IL-6, IL-1β TNF-α and total nitrite generation. Therefore, the effects of the above mentioned medicinal and their active constituents improved neurodegenerative diseases which indicate their therapeutic potential in disorders associated with neuro-inflammation and neurotransmitter deficiency such as AD and depression. © 2018 Center for Food and Biomolecules, National Taiwan University

Item Type: Article
Additional Information: Cited By :6 Export Date: 16 February 2020 Correspondence Address: Khazdair, M.R.; Neurogenic Inflammation Research Centre, Mashhad University of Medical SciencesIran; email: khazdeirmr921@mums.ac.ir
Uncontrolled Keywords: Medicinal plant Memory Nervous system Spice Traditional medicine
Subjects: WZ History of Medicine
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib1 lib1
Date Deposited: 21 Jun 2020 06:50
Last Modified: 21 Jun 2020 06:50
URI: http://eprints.mums.ac.ir/id/eprint/18468

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