Etiology of renal replacement therapy in Iran

Morovatdar, N. and Tayebi Nasrabad, G. and Tsarouhas, K. and Rezaee, R. (2019) Etiology of renal replacement therapy in Iran. International Journal of Nephrology, 2019.

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Introduction. End-stage renal disease (ESRD) is one of the most common life-threatening diseases. In the past two decades, several factors were held responsible as the cause of this condition. The present study aimed to determine the causes of ESRD in the province of Khorasan Razavi, Iran. Materials and Methods. This cross-sectional study was conducted on 2404 ESRD patients who referred to 39 hemodialysis centers in Khorasan Razavi province, Iran, and were registered in the Mashhad University of Medical Sciences (MUMS), between 2000 and December 2018. Sociodemographic data and causes of ESRD were extracted from data registry. Results. The mean age at onset of hemodialysis for 2404 patients was 52.8 ± 16.4 years, and 57.1 of the patients were male. Clinical profile of hypertension (28.3) and diabetes mellitus (24.8) were the most common known causes of ESRD in our patients. Hypertension was more prevalent in male patients compared with females (30 vs 25, respectively) while diabetes was more prevalent in females compared with males (25.4 vs 24.4, respectively), p=0.009. Educational level was significantly associated with the cause of ESRD (p<0.001). Age of onset of ESRD in hypertensive patients was significantly lower compared with diabetic patients (51.5 ± 16.3 vs 58.28 ± 12.9 years, respectively; p<0.001). Conclusions. In the current study, the most common causes of ESRD were hypertension and diabetes mellitus. Primary prevention of hypertension and diabetes and proper treatment must be considered to reduce the burden of ESRD in Iran. © 2019 Negar Morovatdar et al.

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Morovatdar, N.; Clinical Research Unit, Imam Reza Hospital, Faculty of Medicine, Mashhad University of Medical SciencesIran; email:
Subjects: WJ Urogenital System
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib1 lib1
Date Deposited: 21 Jun 2020 09:24
Last Modified: 21 Jun 2020 09:24

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