A prospective randomized study comparing incision and curettage with injection of triamcinolone acetonide for chronic chalazia

Nabie, R. and Soleimani, H. and Nikniaz, L. and Raoufi, S. and Hassanpour, E. and Mamaghani, S. and Bahremani, E. (2019) A prospective randomized study comparing incision and curettage with injection of triamcinolone acetonide for chronic chalazia. Journal of Current Ophthalmology, 31 (3). pp. 323-326.

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Abstract

Purpose: To compare outcomes of intralesional triamcinolone acetonide (TA) injection and incision and curettage (I&C) in the treatment of chronic chalazion. Methods: Patients with chronic chalazion were randomized in two groups. The patients in the TA received an intralesional injection of TA and patients in the I&C underwent I&C. The patients were followed up 3, 7, 14, 21, 28, and 45 days after the procedures. We defined success as 90 regression in the size of the lesion. Results: There were 26 patients in the TA and 25 patients in the I&C enrolled in this study. Complete resolution was achieved in 16 patients (61.5) in the TA group and 21 patients (84) in the I&C (P = 0.072). Sex, initial size, and chalazion location did not influence treatment success in either group (P > 0.05). Lesion recurrence occurred in 9 patients (34.61) in the TA group and 2 (8) in the I&C (P = 0.04). The average times to resolution were 8.8 ± 5.6 and 5.1 ± 4.5 days in the first and second groups, respectively (P = 0.03). Drug deposition occurred in 24 (92.3) patients in the TA group, and ecchymosis occurred in 14 (56) patients in the I&C (P = 0.004) group. Intraocular pressure (IOP) in the TA group and visual acuity (VA) in both groups remained unchanged. Conclusions: Both TA injection and I&C modalities are effective in the treatment of chronic chalazia. Advantages of I&C in comparison to TA include less recurrence, shorter duration of complications, and a higher success rate. © 2019 Iranian Society of Ophthalmology

Item Type: Article
Additional Information: Export Date: 16 February 2020 Correspondence Address: Nabie, R.; Nikookari Eye Center, Abbasi Street, Iran; email: rnabie@yahoo.com
Uncontrolled Keywords: Chalazion Curettage Triamcinolone triamcinolone acetonide adult Article chronic disease controlled study disease duration ecchymosis female follow up human incision injection intraocular pressure major clinical study male postoperative complication prospective study randomized controlled trial recurrent disease sex ratio visual acuity
Subjects: WW Ophthalmology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib1 lib1
Date Deposited: 21 Jun 2020 09:28
Last Modified: 21 Jun 2020 09:28
URI: http://eprints.mums.ac.ir/id/eprint/18554

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