The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer

Bagheri, R. and RajabiMashhadi, M. T. and Ghazvini, K. and Asnaashari, A. and Zahediyan, A. and Sahebi, M. A. (2012) The effect of neoadjuvant chemoradiotherapy on airway colonization and postoperative respiratory complications in patients undergoing oesophagectomy for oesophageal cancer. Interactive Cardiovascular and Thoracic Surgery, 14 (6). pp. 725-728.

[img] Text
ivs009.pdf

Download (100kB)

Abstract

Respiratory complication is one of the important postoperative complications of oesophageal cancer. The aim of this study was to evaluate whether neoadjuvant chemotherapy before surgery is effective for postoperative respiratory complications. In this study, patients with oesophageal cancer were divided into two group: one with neoadjuvant therapy and the other without neoadjuvant therapy. Before surgery, they all underwent bronchoscopy and bronchoalveolar lavage. We evaluated respiratory complications and the effects of preoperative neoadjuvant therapy. Forty patients (M/F = 23/17 and mean age 61 years) were enrolled in this study. Twentytwo cases had cancer in the middle part and 18 in the lower part of the oesophagus. Significant correlation was observed between the number of positive micro-organism and difficulty in weaning and receiving neoadjuvant therapy. But no significant correlation was found between neoadjuvant therapy and respiratory complications. © 2012 The Author.

Item Type: Article
Additional Information: Cited By :8 Export Date: 16 February 2020 CODEN: ICTSC Correspondence Address: Bagheri, R.; Faculty of Medicine, Mashhad University of Medical Sciences, Ghaem Hospital, Mashhad, Iran; email: bagherir@mums.ac.ir
Uncontrolled Keywords: Airway colonization Neoadjuvant therapy Oesophageal cancer Pulmonary complications cisplatin fluorouracil adjuvant chemoradiotherapy adjuvant therapy adult article atelectasis bronchoscopy cancer localization cancer radiotherapy clinical article controlled study esophagus cancer esophagus resection female human lung complication lung lavage male microbial colonization nonhuman postoperative complication preoperative treatment priority journal randomized controlled trial Antineoplastic Combined Chemotherapy Protocols Bronchoalveolar Lavage Chemoradiotherapy, Adjuvant Esophageal Neoplasms Esophagectomy Hospital Mortality Humans Iran Middle Aged Radiotherapy Dosage Respiration Disorders Respiratory Tract Infections Risk Assessment Risk Factors Time Factors Treatment Outcome Ventilator Weaning
Subjects: WO Surgery
QV pharmacology
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 11 May 2020 05:43
Last Modified: 11 May 2020 05:43
URI: http://eprints.mums.ac.ir/id/eprint/18774

Actions (login required)

View Item View Item