A retrospective analysis of rectal and bladder dose for gynecological brachytherapy treatments with GZP6 HDR afterloading system

Bahreyni Toossi, M. T. and Ghorbani, M. and Makhdoumi, Y. and Taheri, M. and Homaee Shandiz, F. and Zahed Anaraki, S. and Soleimani Meigooni, A. (2012) A retrospective analysis of rectal and bladder dose for gynecological brachytherapy treatments with GZP6 HDR afterloading system. Reports of Practical Oncology and Radiotherapy, 17 (6). pp. 352-357.

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Aim: The aim of this work is to evaluate rectal and bladder dose for the patients treated for gynecological cancers. Background: The GZP6 high dose rate brachytherapy system has been recently introduced to a number of radiation therapy departments in Iran, for treatment of various tumor sites such as cervix and vagina. Materials and methods: Our analysis was based on dose measurements for 40 insertions in 28 patients, treated by a GZP6 unit between June 2009 and November 2010. Treatments consisted of combined teletherapy and intracavitary brachytherapy. In vivo dosimetry was performed with TLD-400 chips and TLD-100 microcubes in the rectum and bladder. Results: The average of maximum rectal and bladder dose values were found to be 7.62. Gy (range 1.72-18.55. Gy) and 5.17. Gy (range 0.72-15.85. Gy), respectively. It has been recommended by the ICRU that the maximum dose to the rectum and bladder in intracavitary treatment of vaginal or cervical cancer should be lower than 80 of the prescribed dose to point A in the Manchester system. In this study, of the total number of 40 insertions, maximum rectal dose in 29 insertions (72.5 of treatment sessions) and maximum bladder dose in 18 insertions (45 of treatments sessions) were higher than 80 of the prescribed dose to the point of dose prescription. Conclusion: In vivo dosimetry for patients undergoing treatment by GZP6 brachytherapy system can be used for evaluation of the quality of brachytherapy treatments by this system. This information could be used as a base for developing the strategy for treatment of patients treated with GZP6 system. © 2012 Greater Poland Cancer Centre.

Item Type: Article
Additional Information: Cited By :3 Export Date: 16 February 2020 CODEN: RPORA Correspondence Address: Ghorbani, M.; Vice Chancellery of Research and Technology, North Khorasan University of Medical Sciences, South Shariati No. 7, Postal Zip Code: 94149-53535, Bojnurd, North Khorasan, Iran; email: mhdghorbani@gmail.com
Uncontrolled Keywords: Bladder dose Brachytherapy GZP6 afterloading unit Rectal dose article bladder cancer radiotherapy clinical article clinical evaluation dosimetry female health care quality human in vivo study Iran pilot study prescription radiation dose rectum retrospective study teletherapy tumor localization uterine cervix cancer vagina cancer
Subjects: WN Radiology . Diagnostic Imaging
QZ pathology-neoplasms-Genetics
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 11 May 2020 06:24
Last Modified: 11 May 2020 06:24
URI: http://eprints.mums.ac.ir/id/eprint/18777

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