Comparative study of the antimicrobial effect of three irrigant solutions (chlorhexidine, sodium hypochlorite and chlorhexidinated MUMS)

Bidar, M. and Hooshiar, S. and Naderinasab, M. and Moazzami, M. and Orafaee, H. and Naghavi, N. and Jafarzadeh, H. (2012) Comparative study of the antimicrobial effect of three irrigant solutions (chlorhexidine, sodium hypochlorite and chlorhexidinated MUMS). Journal of Contemporary Dental Practice, 13 (4). pp. 436-439.

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Aim: To compare the antimicrobial effect of 2 chlorhexidine, 2.5 sodium hypochlorite and MUMS containing 2 chlorhexidine. Materials and methods: All of the above irrigants were examined on Enterococcus faecalis, Streptococcus mutans, Candida albicans, Lactobacillus casei and E.coli. A total of 0.5 CC of each solution and 0.5 CC of McFarland solution bacterium were added to each examination tube. After 15, 30 and 45 minutes, colony count was performed for each tube. The difference in the number of bacteria indicated the effect taken by disinfectant material. Results: MUMS containing chlorhexidine showed the antimicrobial properties just like chlorhexidine's effect against E.coli, Streptococcus mutans, Candida albicans, Enterococcus faecalis and Lactobacillus casei in preventing these entiremicroorganisms to incubate. Sodium hypochlorite was not effective against Enterococcus faecalis and Candida albicans incubated in 15, 30 and 45 minutes and Enterococcus faecalis in 15 minutes. Conclusion: MUMS has antimicrobial properties similar to chlorhexidine. Clinical significance: As MUMS containing chlorhexidine can transfer chlorhexidine through its own surfactant around apical area and it canopen the dentinal tubules by its own chelator for more penetration of chlorhexidine, it may be a choice for canal irrigation.

Item Type: Article
Additional Information: Cited By :5 Export Date: 16 February 2020 Correspondence Address: Jafarzadeh, H.; Department of Endodontics, Dental Research Center, Faculty of Dentistry, Mashhad University of Medical Sciences, PO Box: 91735-984, Vakilabad Blvd, Mashhad, Iran; email:
Uncontrolled Keywords: Antimicrobial activity Chlorhexidine Irrigant Microbial study Sodium hypochlorite
Subjects: QV pharmacology
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 03 May 2020 08:50
Last Modified: 03 May 2020 08:50

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