Combined chlorhexidine-sodiumfluoride mouthrinse for orthodontic patients: Clinical and microbiological study

Dehghani, M. and Abtahi, M. and Sadeghian, H. and Shafaee, H. and Tanbakuchi, B. (2015) Combined chlorhexidine-sodiumfluoride mouthrinse for orthodontic patients: Clinical and microbiological study. Journal of Clinical and Experimental Dentistry, 7 (5). e569-e575.

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Background: Orthodontic appliances impede good dental plaque control by brushing. Antimicrobial mouth rinses were suggested to improve this performance. We therefore aimed to investigate the effects of combined mouthrinse containing chlorhexidine (CHX) and sodium fluoride (NaF) on clinical oral hygiene parameters, and plaque bacterial level. Material and Methods: In this double-blind clinical study, 60 fixed orthodontic patients aged 14-25 years were randomly assigned to one of four mouthrinses groups: 1-combined CHX/NaF 2-CHX 0.06 3-NaF0.05 4-placebo. Following baseline examination patients were instructed to use the assigned mouthrinse twice daily for 21 days. Bleeding index (BI), modified gingival index (MGI) and plaque index (PI) were determined at the baselineand after three weeks of rinsing. Samples from supragingival plaque were obtained for the assessment of total bacterial, Streptococcus mutans and Lactobacilli colony counts. Data were analyzed by Wilcoxon, Kruskal-Wallis, and Mann-Whitney tests. Results: Clinical parameters; All three active mouth rinses induced significant improvements of BI, MGI, and PI (P<0.05). Results of CHX/NaF were slightly, but not significantly, better than CHX. CHX/NaF and CHX induced significantly more changes than NaF and placebo. Microbiological measurements; Except placebo, other mouthrinses reduced total bacterial, Streptococcus mutans, and Lactobacilli counts significantly (P<0.05). CHX/NaF acted against Lactobacilli significantly more than others. Conclusions: Adding CHX0.06/NaF0.05 combined mouth rinse to daily oral hygiene regimen of orthodontic patients significantly improved oral hygiene status. Effect of this combined mouth rinse on dental plaque Lactobacilli was remarkable. However, large controlled trials could provide more definitive evidence. © Medicina Oral S. L.

Item Type: Article
Additional Information: Cited By :8 Export Date: 16 February 2020 Correspondence Address: Abtahi, M.; Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Park Square, Vakilabad Blvd., Iran; email:
Uncontrolled Keywords: Chlorhexidine Fluoride Mouthrinse Plaque
Subjects: WU Dentistry. Oral surgery
Divisions: Mashhad University of Medical Sciences
Depositing User: mr lib5 lib5
Date Deposited: 10 May 2020 16:13
Last Modified: 10 May 2020 16:13

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